Funding search · EIN 043673104 · Osprey, FL
Phelan McDermid Syndrome Foundation
A grantmaking public charity (files IRS Form 990, Schedule I). Charities like this often run real grant programs with application cycles.
- 9
- grants reported
- $612,292
- total given
- 2022–2025
- filing years
- $55,000
- median grant
Based on grants this organization reported to the IRS for tax years 2022–2025. This is what they filed, not a complete record of their giving, and recent years may be incomplete because filings lag.
Funder website ↗Full IRS filings ↗How this is builtReport an error
Funding pattern
What this funder pays for, at what size, and how to position adjacent work. Read from their filings, with every number checked against the record.
Sign in to analyze this funder’s giving pattern. Free in early access.
8 grants matching “Down syndrome” · $602,292
- $100,000
Children'S Hospital of Los Angeles · Los Angeles, CA · 2025
To identify diagnostic biomarkers in up to 30 individuals with Phelan-McDermid syndrome who present with neuropsychiatric disease. To determine whether these individuals exhibit distinct cytokine, proteomic, and metabol… read allTo identify diagnostic biomarkers in up to 30 individuals with Phelan-McDermid syndrome who present with neuropsychiatric disease. To determine whether these individuals exhibit distinct cytokine, proteomic, and metabolomic profiles in the serum and cerebrospinal fluid indicative of systemic and/or central inflammation. To evaluate markers of cortical and white matter disruption using magnetic resonance imaging and electroencephalography. less
- $116,392
Boston Children'S Hospital · Boston, MA · 2024
To support the conclusion of the second phase of the Developmental Synaptopathies Consortium's Phelan-McDermid syndrome natural history study, including Boston Children's Hospital personnel costs and subawards to Icahn … read allTo support the conclusion of the second phase of the Developmental Synaptopathies Consortium's Phelan-McDermid syndrome natural history study, including Boston Children's Hospital personnel costs and subawards to Icahn Mount Sinai Medical Center and Rush University for personnel costs as well. less
- $100,000
Seaver Autism Center · New York, NY · 2024
To fund the further development of the Phelan-McDermid syndrome Inventory for Psychiatric Symptoms (PIPS) tool, to better support individuals with Phelan McDermid syndrome and their caregivers with managing and interven… read allTo fund the further development of the Phelan-McDermid syndrome Inventory for Psychiatric Symptoms (PIPS) tool, to better support individuals with Phelan McDermid syndrome and their caregivers with managing and intervening in neuropsychiatric episodes experienced by these individuals. less
- $55,000
Northeastern University · Boston, MA · 2024
To support a project seeking to expand a new natural communication sampling protocol called ROSCO (Rapid Online Sample of Communication). ROSCO is designed to elicit meaningful samples of communication from individuals … read allTo support a project seeking to expand a new natural communication sampling protocol called ROSCO (Rapid Online Sample of Communication). ROSCO is designed to elicit meaningful samples of communication from individuals with Phelan McDermid syndrome via online-video platforms like Zoom in approximately 15 minutes. This study will validate the ROSCO paradigm with the Phelan McDermid syndrome population longitudinally, using repeated samples to establish reliability and sensitivity to communication change over time. less
- $100,000
Children'S Hospital Corporation · Boston, MA · 2023
To understand whether people with Phelan-McDermid syndrome, particularly those with severe neuropsychiatric illness (SNPI) -- have underlying differences in their immune system that might guide treatment.
- $55,000
Clemson University Foundation · Clemson, SC · 2023
To study the response of cells from individuals with Phelan-McDermid syndrome to candidate therapeutics/treatments (such as Insulin-like Growth Factor 1 and human growth hormone) and identify subgroups in the Phelan-McD… read allTo study the response of cells from individuals with Phelan-McDermid syndrome to candidate therapeutics/treatments (such as Insulin-like Growth Factor 1 and human growth hormone) and identify subgroups in the Phelan-McDermid syndrome population that will potentially respond better or worse to the selected compounds. less
- $55,000
University of Miami · Coral Gables, FL · 2023
To develop an alternative objective measure of Gastrointestinal motility (GI transit) in individuals with Phelan-McDermid syndrome. Muffins with blue dye will be ingested by individuals with Phelan-McDermid syndrome and… read allTo develop an alternative objective measure of Gastrointestinal motility (GI transit) in individuals with Phelan-McDermid syndrome. Muffins with blue dye will be ingested by individuals with Phelan-McDermid syndrome and caregivers will use a mobile app to track and report GI transit time. less
- $20,900
Icahn School of Medicine at Mount Sinai · New York, NY · 2022
To define and retrospectively characterize the neurobehavioral profile of individuals with Phelan-McDermid syndrome and neuropsychiatric decompensation. To develop clinician and caregiver survey tools for qualitative as… read allTo define and retrospectively characterize the neurobehavioral profile of individuals with Phelan-McDermid syndrome and neuropsychiatric decompensation. To develop clinician and caregiver survey tools for qualitative assessment of clinical outcomes based on recommendations from the Phelan-McDermid syndrome Neuropsychiatric Consultation Group. less
Grant history
All 9 reported grants, largest first.
- $116,392
Boston Children'S Hospital · Boston, MA · 2024
To support the conclusion of the second phase of the Developmental Synaptopathies Consortium's Phelan-McDermid syndrome natural history study, including Boston Children's Hospital personnel costs and subawards to Icahn … read allTo support the conclusion of the second phase of the Developmental Synaptopathies Consortium's Phelan-McDermid syndrome natural history study, including Boston Children's Hospital personnel costs and subawards to Icahn Mount Sinai Medical Center and Rush University for personnel costs as well. less
- $100,000
Children'S Hospital of Los Angeles · Los Angeles, CA · 2025
To identify diagnostic biomarkers in up to 30 individuals with Phelan-McDermid syndrome who present with neuropsychiatric disease. To determine whether these individuals exhibit distinct cytokine, proteomic, and metabol… read allTo identify diagnostic biomarkers in up to 30 individuals with Phelan-McDermid syndrome who present with neuropsychiatric disease. To determine whether these individuals exhibit distinct cytokine, proteomic, and metabolomic profiles in the serum and cerebrospinal fluid indicative of systemic and/or central inflammation. To evaluate markers of cortical and white matter disruption using magnetic resonance imaging and electroencephalography. less
- $100,000
Seaver Autism Center · New York, NY · 2024
To fund the further development of the Phelan-McDermid syndrome Inventory for Psychiatric Symptoms (PIPS) tool, to better support individuals with Phelan McDermid syndrome and their caregivers with managing and interven… read allTo fund the further development of the Phelan-McDermid syndrome Inventory for Psychiatric Symptoms (PIPS) tool, to better support individuals with Phelan McDermid syndrome and their caregivers with managing and intervening in neuropsychiatric episodes experienced by these individuals. less
- $100,000
Children'S Hospital Corporation · Boston, MA · 2023
To understand whether people with Phelan-McDermid syndrome, particularly those with severe neuropsychiatric illness (SNPI) -- have underlying differences in their immune system that might guide treatment.
- $55,000
Northeastern University · Boston, MA · 2024
To support a project seeking to expand a new natural communication sampling protocol called ROSCO (Rapid Online Sample of Communication). ROSCO is designed to elicit meaningful samples of communication from individuals … read allTo support a project seeking to expand a new natural communication sampling protocol called ROSCO (Rapid Online Sample of Communication). ROSCO is designed to elicit meaningful samples of communication from individuals with Phelan McDermid syndrome via online-video platforms like Zoom in approximately 15 minutes. This study will validate the ROSCO paradigm with the Phelan McDermid syndrome population longitudinally, using repeated samples to establish reliability and sensitivity to communication change over time. less
- $55,000
Clemson University Foundation · Clemson, SC · 2023
To study the response of cells from individuals with Phelan-McDermid syndrome to candidate therapeutics/treatments (such as Insulin-like Growth Factor 1 and human growth hormone) and identify subgroups in the Phelan-McD… read allTo study the response of cells from individuals with Phelan-McDermid syndrome to candidate therapeutics/treatments (such as Insulin-like Growth Factor 1 and human growth hormone) and identify subgroups in the Phelan-McDermid syndrome population that will potentially respond better or worse to the selected compounds. less
- $55,000
University of Miami · Coral Gables, FL · 2023
To develop an alternative objective measure of Gastrointestinal motility (GI transit) in individuals with Phelan-McDermid syndrome. Muffins with blue dye will be ingested by individuals with Phelan-McDermid syndrome and… read allTo develop an alternative objective measure of Gastrointestinal motility (GI transit) in individuals with Phelan-McDermid syndrome. Muffins with blue dye will be ingested by individuals with Phelan-McDermid syndrome and caregivers will use a mobile app to track and report GI transit time. less
- $20,900
Icahn School of Medicine at Mount Sinai · New York, NY · 2022
To define and retrospectively characterize the neurobehavioral profile of individuals with Phelan-McDermid syndrome and neuropsychiatric decompensation. To develop clinician and caregiver survey tools for qualitative as… read allTo define and retrospectively characterize the neurobehavioral profile of individuals with Phelan-McDermid syndrome and neuropsychiatric decompensation. To develop clinician and caregiver survey tools for qualitative assessment of clinical outcomes based on recommendations from the Phelan-McDermid syndrome Neuropsychiatric Consultation Group. less
- $10,000
Autism Science Foundation · Scarsdale, NY · 2023
To model neuroinflammation and neuropsychiatric regression in profound autism.
Who else funds this kind of work
Same state
- Dechomai Foundation224 grants · $1.36B
- Ncf Charitable Trust43 grants · $1.44B
- Baptist Health South Florida510 grants · $1.14B
Similar grant size
- The Ojc Fund12,726 grants · $1.41B
- The Robert Wood Johnson Foundation13,555 grants · $2.27B
- Ohio Child Care Resource and Referral16,278 grants · $1.08B
Grants already paid are the record; PaperOrbit reads your paper and finds the funders whose record matches it — then explains why.
Search funders like this oneSource: IRS Form 990, Schedule I, as filed by this organization. These are grants already paid. Grants paid directly to individuals are reported to the IRS only as totals, so they do not appear as named lines here.