Funding search · EIN 137184401 · New York, NY

The Leona M and Harry B Helmsley

A private foundation (files IRS Form 990-PF). Most private foundations do not take unsolicited applications; the route in is usually a program officer.

2,251
grants reported
$1.69B
total given
2021–2024
filing years
$393,039
median grant

Based on grants this organization reported to the IRS for tax years 20212024. This is what they filed, not a complete record of their giving, and recent years may be incomplete because filings lag.

What they fund

diseasecrohnshealthdiabetescentertypeultrasoundcare

Funder website ↗Full IRS filings ↗How this is builtReport an error

Funding pattern

What this funder pays for, at what size, and how to position adjacent work. Read from their filings, with every number checked against the record.

Where the money goes

  • Type 1 diabetes care, prevention trials, and global access
  • Crohn's disease mechanism, diagnostics, and therapeutic research
  • Rural US hospital equipment and capital, especially Upper Midwest and Hawaii
  • Israeli hospital construction and university science buildings
  • Sub-Saharan Africa health systems, WASH, and maternal-child care
  • Emergency and telehealth systems: stroke, ECMO, point-of-care ultrasound

Typical grant

Median grant is about $393,000, with the middle half between $156,000 and $927,000. The seven-figure checks go to two things: bricks and equipment (hospital wings in Israel, cancer centers in Hawaii, ultrasound fleets across North Dakota and Minnesota) and multi-year research or scale-up commitments in T1D and Crohn's, often $1.5M to $5M. Repeat giving is the norm, and the same recipient frequently appears two or three times in one year as a multi-payment award.

Their words

Phrases from their own grant descriptions, worth speaking back to them.

  • T1D
  • Crohn's disease
  • ultrasound initiative
  • scaling
  • quality improvement
  • access to primary care

Positioning adjacent work

  • Frame diabetes work as T1D specifically, tied to outcomes, registries, or quality improvement collaboratives.
  • For Crohn's, propose mechanistic or precision-diagnostic science with a defined trial or dataset endpoint.
  • Rural health proposals should name equipment, training, and geography: Dakotas, Minnesota, Montana, Hawaii.
  • Ask $1.5M to $3M multi-year for research; capital requests run $2M to $5M.

Worth knowing: Giving is concentrated in a small set of long-term partners (T1D Exchange, Blue Circle Health, Helmholtz Zentrum Munchen, Clalit, Billings Clinic, American Heart Association) and reads as relationship-driven and invited rather than competitive. Beyond the coastal research hubs in NY, MA, and CA, the money follows named geographies: rural Upper Midwest, Hawaii, Israel, and Ghana-centered Africa work.

149 grants matching “cell · $49.6M

  • $502,750

    Regents of the University of Minnesota · Minneapolis, MN · 2024

    Engineering antigen-specific regulatory t cells for use in type 1 diabetes (phase 3)

  • $501,000

    The Regents of the University of Colorado Denver · Aurora, CO · 2024

    T and b cell receptor atlas across tissues and stages of type 1 diabetes

  • $485,616

    Georgia Tech Research Corporation · Atlanta, GA · 2024

    Longitudinal tracking and reference-based interpretation of single-cell characteristics in treatment nave patients with crohns disease

  • $426,571

    Katholieke Universiteit Te Leuven · 2024

    Targeting chronic inflammation and tissue remodelling in crohn's disease with engineered t cells

  • $407,000

    Trustees of the University of Pennsylvania · Philadelphia, PA · 2024

    Engineering car regulatory t cells to provide durable tolerance to allogenic islet transplants

  • $402,672

    Genome Research Limited for the Wellcome Sanger Institute · 2024

    Scibd-response massive-scale single-cell rna-sequencing to identify transcriptomic predictors of response to biologic therapies in crohns disease

  • $384,292

    King'S College London · 2024

    Resolving harmful accumulation of innate lymphoid cells during crohns disease.

  • $368,500

    The City of Hope · Duarte, CA · 2024

    Cd318 mediated regulation of islet autoantigen specific t cell immunity

  • $364,886

    Vanderbilt University Medical Center · Nashville, TN · 2024

    Expansion of pancreatlas connectivity platform and phenotyping of handel samples by cutting-edge single cell multiome technology

  • $362,460

    Institut National De La Sante Et De La Recherche Medicale · 2024

    From benign islet autoimmunity to type 1 diabetes hla-a- vs. Hla-b-restricted cd8 t-cell biomarkers of progression

  • $330,000

    Washington University · Saint Louis, MO · 2024

    Restoration of normal glucagon secretory dynamics by direct manipulation of alpha cell signaling

  • $318,978

    Palo Alto Veterans Institute for Research · Palo Alto, CA · 2024

    Cell atlas of human intestinal lymphoid tissues and changes in crohn's disease

  • $315,380

    Ballad Research Institute · San Diego, CA · 2024

    Cd127-high t-cell populations in autoantibody positive children

  • $300,000

    The Regents of the University of Colorado Denver · Aurora, CO · 2024

    Mapping the b cell heterogeneity in type 1 diabetes at the single-cell level

  • $298,224

    St Vincent'S Institute of Medical Research · 2024

    Which checkpoints maintain immune tolerance to beta-cells in genetically at-risk people who dont have t1d?

  • $291,029

    The Regents of the University of Colorado Denver · Aurora, CO · 2024

    Defining human islet myeloid cell populations through progression of type 1 diabetes

  • $290,806

    University of Utah · Salt Lake City, UT · 2024

    Induction of peripheral tolerance to beta cell antigens by specific targeting of langerin dendritic cells

  • $275,861

    Duke University · Durham, NC · 2024

    Novel assays for proglucagon peptides to understand alpha cell function in health and diabetes

  • $275,000

    Vanderbilt University · Nashville, TN · 2024

    Normalizing hypoglycemia-induced glucagon secretion in t1d through pharmacological restoration of alpha-cell calcium handling

  • $275,000

    Vanderbilt University Medical Center · Nashville, TN · 2024

    Defining molecular mechanisms of cell dysfunction in type 1 diabetes to develop new approaches to prevent hypoglycemia

  • $247,813

    University of Exeter · 2024

    B cell signatures in type 1 diabetes

  • $247,023

    University of Miami · Coral Gables, FL · 2024

    Develop a new method of studying alpha cell function in pancreatic slices

  • $237,102

    University of Pittsburgh · Pittsburgh, PA · 2024

    Single cell multimodal omics analysis of colonoscopic biopsy-derived immune cells in crohns disease

  • $221,500

    Hebrew University of Jerusalem · 2024

    Methylation patterns of cell-free dna as a novel biomarker in crohns disease

  • $213,602

    Universite Libre De Bruxelles · 2024

    Generation of new anti- fxyd2a probes and preclinical validation for human beta cell imaging

  • $213,278

    Universite Libre De Bruxelles · 2024

    Studying the selective b cell sensitivity to a homozygous pd-l1 mutation in neonatal diabetes

  • $209,222

    The University of Edinburgh · 2024

    Human gut cell atlas - normal intestine and crohn's disease

  • $187,672

    Genome Research Limited for the Wellcome Sanger Institute · 2024

    Scibd-response massive-scale single-cell rna-sequencing to identify transcriptomic predictors of response to biologic therapies in crohns disease

  • $135,722

    Herlev Og Gentofte Hospital · 2024

    Interaction between amino acids and glucose-dependent insulinotropic polypeptide in pancreatic alpha cells

  • $58,372

    Trustees of Indiana University · Bloomington, ID · 2024

    Targeting metabolic drivers of b cell differentiation in type 1 diabetes

  • $55,571

    University of Exeter · 2024

    Advancing b-cell specific therapy by identifying b-cell reactive high affinity t cell receptors

  • $50,000

    Human Cell Atlas Incorporated · Cambridge, MA · 2024

    2024 human cell atlas general meeting

  • $28,108

    Medical University of South Carolina · Charleston, SC · 2024

    Engineered dendritic cell based robust antigen specific therapy for type 1 diabetes

  • $1.1M

    The University of Manchester · 2023

    A map of the intestine following regulatory t cell infusion into patients with active crohns disease at single-cell and spatial resolution

  • $502,750

    Regents of the University of Minnesota · Minneapolis, MN · 2023

    Engineering antigen-specific regulatory t cells for use in type 1 diabetes (phase 3)

  • $501,000

    The Regents of the University of Colorado Denver · Aurora, CO · 2023

    T and b cell receptor atlas across tissues and stages of type 1 diabetes

  • $496,512

    Vanderbilt University Medical Center · Nashville, TN · 2023

    Development of an administrative core and collaborative data repository for the gut cell atlas

  • $485,617

    Georgia Tech Research Corporation · Atlanta, GA · 2023

    Longitudinal tracking and reference-based interpretation of single-cell characteristics in treatment nave patients with crohns disease

  • $480,848

    Georgia Tech Research Corporation · Atlanta, GA · 2023

    Longitudinal tracking and reference-based interpretation of single-cell characteristics in treatment nave patients with crohns disease

  • $447,521

    King'S College London · 2023

    Resolving harmful accumulation of innate lymphoid cells during crohns disease.

  • $444,246

    The University of Edinburgh · 2023

    Human gut cell atlas - normal intestine and crohn's disease

  • $412,500

    Medical University of South Carolina · Charleston, SC · 2023

    Engineered dendritic cell based robust antigen specific therapy for type 1 diabetes

  • $407,000

    Trustees of the University of Pennsylvania · Philadelphia, PA · 2023

    Engineering car regulatory t cells to provide durable tolerance to allogenic islet transplants

  • $404,688

    Icahn School of Medicine at Mount Sinai · New York City, NY · 2023

    Next phase of stem cell transplant for refractory crohns disease

  • $397,123

    Genome Research Limited for the Wellcome Sanger Institute · 2023

    Scibd-response: massive-scale single-cell rna-sequencing to identify transcriptomic predictors of response to biologic therapies in crohns disease

  • $374,591

    Children'S Hospital Corporation · Boston, MA · 2023

    Molecular and spatial single-cell remodeling in pediatric crohns disease

  • $362,703

    Hebrew University of Jerusalem · 2023

    Methylation patterns of cell-free dna as a novel biomarker in crohns disease

  • $330,000

    Washington University · Saint Louis, MO · 2023

    Restoration of normal glucagon secretory dynamics by direct manipulation of alpha cell signaling

  • $325,801

    Ballad Research Institute · San Diego, CA · 2023

    Cd127-high t-cell populations as biomarkers

  • $305,349

    Icahn School of Medicine at Mount Sinai · New York City, NY · 2023

    Next phase of stem cell transplant for refractory crohns disease

  • $300,000

    The Regents of the University of Colorado Denver · Aurora, CO · 2023

    Mapping the b cell heterogeneity in type 1 diabetes at the single-cell level

  • $292,821

    Palo Alto Veterans Institute for Research · Palo Alto, CA · 2023

    Cell atlas of human intestinal lymphoid tissues and changes in crohn's disease

  • $290,806

    University of Utah · Salt Lake City, UT · 2023

    Induction of peripheral tolerance to beta cell antigens by specific targeting of langerin+ dendritic cells

  • $290,049

    Vanderbilt University Medical Center · Nashville, TN · 2023

    Combinatorial single cell strategies for a crohn's disease gut cell atlas

  • $280,115

    University of Pittsburgh · Pittsburgh, PA · 2023

    Single cell multimodal omics analysis of colonoscopic biopsy-derived immune cells in crohns disease

  • $275,000

    The University of Texas Southwestern Medical Center · Dallas, TX · 2023

    Immune checkpoint engineered beta cell as an antigen-specific immunotherapy for the treatment of type i diabetes

  • $275,000

    Vanderbilt University · Nashville, TN · 2023

    Normalizing hypoglycemia-induced glucagon secretion in t1d through pharmacological restoration of alpha-cell calcium handling

  • $251,607

    University of Exeter · 2023

    B cell signatures in type 1 diabetes

  • $251,522

    Genome Research Limited for the Wellcome Sanger Institute · 2023

    Scibd-response: massive-scale single-cell rna-sequencing to identify transcriptomic predictors of response to biologic therapies in crohns disease

  • $246,662

    Katholieke Universiteit Te Leuven · 2023

    An enterochromaffin cell and macrophage atlas of the human gut

  • $243,196

    University of Pittsburgh · Pittsburgh, PA · 2023

    Single cell multimodal omics analysis of colonoscopic biopsy-derived immune cells in crohns disease

  • $230,038

    Academisch Ziekenhuis Leiden · 2023

    Safety and efficacy of immune intervention with tolerogenic dendritic cells in patients with early t1d (d-sense ii)

  • $229,347

    Uppsala Universitet · 2023

    Alpha-cell signaling for glucagon secretion

  • $213,582

    Universite Libre De Bruxelles · 2023

    Generation of new anti- fxyd2a probes and preclinical validation for human beta cell imaging

  • $212,881

    The University of Edinburgh · 2023

    Human gut cell atlas - normal intestine and crohn's disease

  • $203,497

    Duke University · Durham, NC · 2023

    Utilizing amino acids and glucose-dependent insulinotropic polypeptide in pancreatic alpha cells to prevent insulin-induced hypoglycemia in t1d

  • $179,714

    The University of Edinburgh · 2023

    Understanding alpha cell dysfunction and correcting glucagon secretion in type 1 diabetes.

  • $170,401

    Vanderbilt University Medical Center · Nashville, TN · 2023

    Defining molecular mechanisms of cell dysfunction in type 1 diabetes to develop newapproaches to prevent hypoglycemia

  • $165,000

    The City of Hope · Duarte, CA · 2023

    Cd318 mediated regulation of islet autoantigen specific t cell immunity

  • $159,623

    The University of Edinburgh · 2023

    Understanding alpha cell dysfunction and correcting glucagon secretion in type 1 diabetes.

  • $145,749

    Vanderbilt University Medical Center · Nashville, TN · 2023

    Expansion of pancreatlas connectivity platform and phenotyping of handel samples by cutting-edge single cell multiome technology

  • $81,534

    Herlev Og Gentofte Hospital · 2023

    Utilization of interaction between amino acids & gip in pancreatic cells

  • $71,503

    Duke University · Durham, NC · 2023

    Utilizing amino acids and glucose-dependent insulinotropic polypeptide in pancreatic alpha cells to prevent insulin-induced hypoglycemia in t1d

  • $50,000

    Human Cell Atlas Incorporated · Cambridge, MA · 2023

    2023 human cell atlas general meeting

  • $1.2M

    The University of Manchester · 2022

    A map of the intestine following regulatory t cell infusion into patients with active crohns disease at single-cell and spatial resolution

  • $671,024

    Hebrew University of Jerusalem · 2022

    Methylation patterns of cell-free dna as a novel biomarker in crohns disease

  • $656,092

    Vanderbilt University Medical Center · Nashville, TN · 2022

    Combinatorial single cell strategies for a crohn's disease gut cell atlas

  • $556,046

    Chancellor Masters & Scholars of the University of Oxford · 2022

    Alpha cell function in people with type 1 diabetes with and without severe hypoglycemia

  • $530,354

    Katholieke Universiteit Leuven · 2022

    An enterochromaffin cell and macrophage atlas of the human gut

  • $500,825

    Palo Alto Veterans Institute for Research · Palo Alto, CA · 2022

    Cell atlas of human intestinal lymphoid tissues and changes in crohn's disease

  • $499,175

    Palo Alto Veterans Institute for Research · Palo Alto, CA · 2022

    Cell atlas of human intestinal lymphoid tissues and changes in crohn's disease

  • $487,806

    The University of Chicago · Chicago, IL · 2022

    A cell atlas of ileal colonic crohn's disease

  • $480,848

    Georgia Tech Research Corporation · Atlanta, GA · 2022

    Longitudinal tracking and reference-based interpretation of single-cell characteristics in treatment nave patients with crohns disease

  • $463,755

    The Broad Institute · Cambridge, MA · 2022

    A human colon and small intestine cell atlas in health and crohns disease

  • $463,751

    The Broad Institute · Cambridge, MA · 2022

    A human colon and small intestine cell atlas in health and crohns disease

  • $444,247

    The University of Edinburgh · 2022

    Human gut cell atlas - normal intestine and crohn's disease

  • $415,688

    Icahn School of Medicine at Mount Sinai · New York City, NY · 2022

    Next phase of stem cell transplant for refractory crohns disease

  • $407,000

    Trustees of the University of Pennsylvania · Philadelphia, PA · 2022

    Engineering car regulatory t cells to provide durable tolerance to allogenic islet transplants

  • $382,456

    The University of Edinburgh · 2022

    Human gut cell atlas - normal intestine and crohn's disease

  • $374,591

    Children'S Hospital Corporation · Boston, MA · 2022

    Molecular and spatial single-cell remodeling in pediatric crohns disease

  • $343,506

    St Vincent'S Institute of Medical Research · 2022

    Which checkpoints maintain immune tolerance to beta-cells in genetically at-risk people who dont have t1d?

  • $330,000

    Washington University · Saint Louis, MO · 2022

    Restoration of normal glucagon secretory dynamics by direct manipulation of alpha cell signaling

  • $300,000

    The Regents of the University of Colorado Denver · Aurora, CO · 2022

    Mapping the b cell heterogeneity in type 1 diabetes at the single-cell level

  • $295,977

    University of Miami · Coral Gables, FL · 2022

    Develop a new method of studying alpha cell function in pancreatic slices

  • $295,566

    Universite Libre De Bruxelles · 2022

    Generation of new anti- fxyd2a probes and preclinical validation for human beta cell imaging

  • $275,000

    Vanderbilt University · Nashville, TN · 2022

    Normalizing hypoglycemia-induced glucagon secretion in t1d through pharmacological restoration of alpha-cell calcium handling

  • $275,000

    Vanderbilt University Medical Center · Nashville, TN · 2022

    Defining molecular mechanisms of cell dysfunction in type 1 diabetes to develop new approaches to prevent hypoglycemia

  • $275,000

    The University of Texas Southwestern Medical Center · Dallas, TX · 2022

    Immune checkpoint engineered beta cell as an antigen-specific immunotherapy for the treatment of type i diabetes

  • $272,676

    Children'S Hospital of Philadelphia · Philadelphia, PA · 2022

    A crohns disease epithelial stem cell atlas: pediatric to adult continuum

  • $250,000

    Regents of the University of Minnesota · Minneapolis, MN · 2022

    Phase 2: engineering antigen-specific regulatory t cells for use in type 1 diabetes

  • $246,663

    Katholieke Universiteit Leuven · 2022

    An enterochromaffin cell and macrophage atlas of the human gut

  • $244,200

    Vanderbilt University Medical Center · Nashville, TN · 2022

    Development of an administrative core and collaborative data repository for the gut cell atlas

  • $239,587

    University of Pittsburgh · Pittsburgh, PA · 2022

    Single cell multimodal omics analysis of colonoscopic biopsy-derived immune cells in crohns disease

  • $190,161

    University of Exeter · 2022

    Advancing b-cell specific therapy by identifying b-cell reactive high affinity t cell receptors

  • $189,596

    Royal Institution for the Advancement of Learning-McGill Uni · 2022

    The human cell atlas: ethics and data governance

  • $164,338

    Institut Nationale De La Sante Et De La Recherche Medicale · 2022

    From benign islet autoimmunity to type 1 diabetes: mechanistic cd8+ t-cell biomarkers of progression

  • $156,725

    Genome Research Limited for the Wellcome Sanger Institute · 2022

    Massive-scale single-cell rna-sequencing to identify transcriptomic predictors of response to biologic therapies in crohns disease

  • $146,933

    Vanderbilt University Medical Center · Nashville, TN · 2022

    Combinatorial single cell strategies for a crohn's disease gut cell atlas

  • $114,365

    Trustees of Indiana University · Bloomington, MI · 2022

    Targeting metabolic drivers of b cell differentiation in type 1 diabetes

  • $76,573

    Uppsala Universitet · 2022

    Alpha-cell signaling for glucagon secretion

  • $57,744

    Herlev Og Gentofte Hospital · 2022

    Utilization of interaction between amino acids & gip in pancreatic cells

  • $951,960

    Georgia Tech Research Corporation · Atlanta, GA · 2021

    Tracking & interpretation of single-cell characteristics in cd patients

  • $775,164

    Hebrew University of Jerusalem · 2021

    Methylation patterns of cell-free dna as a novel biomarker in crohns

  • $719,309

    The Broad Institute · Cambridge, MA · 2021

    Human colon and small intestine cell atlas in health and crohns disease

  • $676,092

    Vanderbilt University Medical Center · Nashville, TN · 2021

    Combinatorial single cell strategies for crohns disease gut cell atlas

  • $664,751

    Icahn School of Medicine at Mount Sinai · New York City, NY · 2021

    Next phase of stem cell transplant for refractory crohns disease

  • $530,355

    Katholieke Universiteit Leuven · 2021

    An enterochromaffin cell and macrophage atlas of the human gut

  • $516,369

    Ballad Research Institute · San Diego, CA · 2021

    Cd127-high t-cell populations as biomarkers

  • $509,159

    Vanderbilt University Medical Center · Nashville, TN · 2021

    Combinatorial single cell strategies for crohns disease gut cell atlas

  • $506,838

    The Chinese University of Hong Kong · 2021

    Maternal transfer of specialized cells for treatment of bowel disease

  • $500,825

    Palo Alto Veterans Institute for Research · Palo Alto, CA · 2021

    Cell atlas of intestinal lymphoid tissues and changes in crohns disease

  • $499,175

    Palo Alto Veterans Institute for Research · Palo Alto, CA · 2021

    Cell atlas of intestinal lymphoid tissues and changes in crohns disease

  • $497,699

    Katholieke Universiteit Leuven · 2021

    An enterochromaffin cell and macrophage atlas of the human gut

  • $487,806

    The University of Chicago · Chicago, IL · 2021

    A cell atlas of the ileal colonic crohns disease

  • $481,225

    The Chinese University of Hong Kong · 2021

    Maternal transfer of specialized cells for treatment of bowel disease

  • $476,319

    The Broad Institute · Cambridge, MA · 2021

    Human colon and small intestine cell atlas in health and crohns disease

  • $424,937

    Children'S Hospital of Philadelphia · Philadelphia, PA · 2021

    Crohns disease epithelial stem cell atlas: pediatric to adult continuum

  • $400,400

    The University of Edinburgh · 2021

    Gca - human gut cell atlas - normal intestine and crohns disease

  • $400,000

    Uppsala University Hospital · 2021

    Isolating islets to understand alpha cell dysfunction and hypoglycemia

  • $373,431

    Institut Nationale De La Sante De La Recherche Medicale · 2021

    Benign islet autoimmunity to t1d: cd8+ t-cell biomarkers of progression

  • $350,000

    Regents of the University of Minnesota · Minneapolis, MN · 2021

    Phase 2: engineering antigen-specific regulatory t cells for t1d

  • $281,734

    Children'S Hospital of Philadelphia · Philadelphia, PA · 2021

    Crohns disease epithelial stem cell atlas: pediatric to adult continuum

  • $275,000

    Duke University · Durham, NC · 2021

    Utilization of interaction between amino acids & gip in pancreatic cells

  • $275,000

    Herlev Og Gentofte Hospital · 2021

    Utilization of interaction between amino acids & gip in pancreatic cells

  • $260,774

    Saint Louis University · Saint Louis, MO · 2021

    Novel target to fight alpha cell dysfunction & stop hypoglycemia in t1d

  • $250,000

    University of Miami · Coral Gables, FL · 2021

    Develop a new method of studying alpha cell function in pancreatic slice

  • $250,000

    Washington University · St Louis, MO · 2021

    Manipulating alpha cell signaling to restore normal glucagon secretory

  • $249,301

    Hebrew University of Jerusalem · 2021

    Methylation patterns of cell-free dna as a novel biomarker in crohns

  • $248,597

    University of Florida · Gainesville, FL · 2021

    T cell receptor sequencing in t1d - biomarker & technology development

  • $231,831

    Vanderbilt University · Nashville, TN · 2021

    Understanding calcium signaling in alpha cells and how they work in t1d

  • $200,000

    Region Hovedstaden · 2021

    Identification/screening of novel glucagonotropic alpha-cell receptors

  • $178,286

    Institut Nationale De La Sante Et De La Recherche Medicale · 2021

    Benign islet autoimmunity to t1d: cd8+ t-cell biomarkers of progression

  • $174,998

    The Milken Institute · Santa Monica, CA · 2021

    Cures for life: patient access to cell and gene therapy

  • $166,933

    Vanderbilt University Medical Center · Nashville, TN · 2021

    Combinatorial single cell strategies for crohns disease gut cell atlas

  • $121,182

    Uppsala Universitet · 2021

    Alpha-cell signaling for glucagon secretion

  • $108,185

    University of California San Francisco · San Francisco, CA · 2021

    Validating a class of drugs that may protect beta cells in t1d

  • $100,000

    The University of Edinburgh · 2021

    Gca - human gut cell atlas - normal intestine and crohns disease

  • $65,459

    The University of Edinburgh · 2021

    Discern alpha cell dysfunction and correcting glucagon secretion in t1d

  • $18,350

    Hebrew University of Jerusalem · 2021

    Methylation patterns of cell-free dna as a novel biomarker in crohns

Top recipients

Repeat recipients are the strongest signal of whether a funder has an open door or quietly re-funds the same organizations.

  • Helmholtz Zentrum Munchen (Gmbh)42 grants · $52.3M
  • Blue Circle Health11 grants · $45.4M
  • Shaare Zedek Medical Center22 grants · $42.6M
  • Clalit Health Services37 grants · $41.7M
  • American Heart Association20 grants · $30.7M
  • Regents of the University of Minnesota16 grants · $30.4M
  • The End Fund4 grants · $30.0M
  • The Regents of the University of Colorado Denver49 grants · $22.5M
  • Mass General Brigham for the Brigham and Women'S Hospital7 grants · $21.5M
  • Catholic Relief Services-Usccb13 grants · $21.4M

Giving over time

$382.7M
2021
$427.5M
2022
$440.0M
2023
$439.5M
2024

Grant history

The 100 largest of 2,251 grants.

  • $22.5M

    The End Fund · New York, NY · 2022

    Neglected tropical disease: reaching the last mile

  • $15.6M

    Blue Circle Health · Wilmington, DE · 2021

    Creation of blue circle health for underserved communities with t1d

  • $12.6M

    Regents of the University of Minnesota · Minneapolis, MN · 2021

    Minnesota first responder aed project

  • $9.9M

    Shaare Zedek Medical Center · 2021

    The helmsley cancer center at shaare zedek medical center jerusalem

  • $9.0M

    Mass General Brigham for the Brigham and Women'S Hospital · Boston, MA · 2023

    Pen-plus expansion

  • $7.0M

    Engineering Ministries International USA · Colorado Springs, CO · 2022

    Alaska wash project

  • $7.0M

    American Heart Association · Dallas, TX · 2024

    American heart association center for telehealth

  • $6.8M

    Mass General Brigham for the Brigham and Women'S Hospital · Boston, MA · 2024

    Accelerating progress and promoting quality t1d care for the poorest billion through the global pen-plus partnership

  • $6.7M

    Engineering Ministries International USA · Colorado Springs, CO · 2021

    Alaska wash project

  • $6.6M

    Nevada Department of Health and Human Services · Carson City, NV · 2022

    Nevada first responder aed project

  • $6.6M

    Geoscience Australia · 2022

    Digital earth africa - sustainable uptake and impact

  • $6.4M

    Commonwealth Healthcare Corporation · 2023

    Cnmi chcc mri/medical equipment upgrade project

  • $6.1M

    Yitzhak Shamir Medical Center · 2022

    Expansion and renovation of the cancer institute at shamir medical center

  • $5.8M

    Ben-Gurion University of the Negev · 2024

    Construction of the leona m. And harry b. Helmsley charitable trust computer science building

  • $5.7M

    Brigham and Women'S Hospital · Boston, MA · 2022

    Pen-plus expansion

  • $5.6M

    Nebraska Department of Health & Human Services · Lincoln, NE · 2021

    Nebraska first responder aed project

  • $5.4M

    Tzafon Medical Center · 2023

    The helmsley rehabilitation center of the north

  • $5.3M

    Iowa Department of Public Health · Des Moines, IA · 2021

    Iowa first responder aed initiative

  • $5.3M

    Hadassah Medical Organization · 2024

    Equipping the new hadassah - helmsley medical center, netivot

  • $5.3M

    Bridges To Prosperity · Denver, CO · 2021

    Transformative connectivity in rural ethiopia

  • $5.2M

    Shaare Zedek Medical Center · 2022

    The helmsley cancer center at shaare zedek medical center jerusalem

  • $5.2M

    Shaare Zedek Medical Center · 2023

    Linear accelerators for the radiotherapy institute

  • $5.1M

    The Baruch Padeh Medical Center Poriya · 2021

    The helmsley rehabilitation center of the north

  • $5.0M

    Regents of the University of Minnesota · Minneapolis, MN · 2022

    Redefining the future of emergency medicine

  • $5.0M

    Billings Clinic Foundation · Billings, MT · 2024

    Billings clinic surgical intensive care unit

  • $5.0M

    Kapiolani Health Foundation · Honolulu, HI · 2024

    Martha b. Smith cancer & infusion center at kapiolani medical center for women & children

  • $5.0M

    Stichting the Ocean Cleanup · 2024

    Develop and scale technologies to rid the oceans of plastics

  • $5.0M

    The Queens Medical Center · Honolulu, HI · 2024

    The queen's medical center - west oahu cancer center expansion

  • $5.0M

    Shaare Zedek Medical Center · 2023

    Development of the helmsley surgical wing

  • $5.0M

    Stichting the Ocean Cleanup · 2023

    Develop and scale technologies to rid the oceans of plastics

  • $5.0M

    Civica Foundation · Lehi, UT · 2021

    Affordable insulin biosimilars

  • $4.9M

    St Rose Dominican Health Foundation · Henderson, NV · 2023

    Dignity health - st. Rose dominican - siena campus ecmo program

  • $4.9M

    Fairview Health Services · Minneapolis, MN · 2023

    Improving survival outcomes through university of minnesota medical center ecmo center of excellence

  • $4.9M

    Regents of the University of Minnesota · Minneapolis, MN · 2023

    Minnesota first responder aed project

  • $4.9M

    Tel Aviv Sourasky Medical Center - Ichilov Hospital · 2024

    Construction of the sheltered -5 floor of the north tower

  • $4.5M

    Baptist Medical Centre · 2024

    Elevating maternal and pediatric healthcare

  • $4.5M

    Blue Circle Health · Wilmington, DE · 2024

    Development of blue circle health

  • $4.5M

    Blue Circle Health · Wilmington, DE · 2024

    Development of blue circle health

  • $4.5M

    The Baruch Padeh Medical Center Poriya · 2022

    The helmsley rehabilitation center of the north

  • $4.4M

    World Health Organization · 2022

    Strengthening the capacity of the global diabetes compact

  • $4.4M

    The Sheba Fund for Health Services and Research (Ra) · 2023

    The helmsley center for innovative surgical training

  • $4.2M

    Altru Health System · Grand Forks, ND · 2024

    Altru health system ultrasound initiative

  • $4.2M

    American Heart Association · Dallas, TX · 2023

    American heart association center for telehealth

  • $4.2M

    Jerusalem College of Technology · 2022

    Helmsley faculty of life and health sciences building

  • $4.1M

    The End Fund · New York, NY · 2023

    Reaching the last mile fund expansion

  • $4.1M

    Zefat Academic College · 2021

    Equipping zefat academic college's inst. For adv. Health training & ed.

  • $4.1M

    Clalit Health Services · 2022

    A new neonatal center for israels southern periphery at soroka medical center

  • $4.0M

    Holy Rosary Healthcare Foundation · Miles City, MT · 2022

    Holy rosary healthcare comprehensive cancer center

  • $4.0M

    Blue Circle Health · Wilmington, DE · 2024

    Development of blue circle health

  • $3.9M

    Wilcox Health Foundation · Lihue, HI · 2024

    Wilcox medical center equipment revitalization project

  • $3.9M

    Clalit Health Services · 2021

    Medical equipment for carmel medical center in haifa, israel

  • $3.9M

    Hadassah Medical Organization · 2022

    Creating and equipping a new comprehensive diagnostic and interventional imaging center

  • $3.8M

    Clalit Health Services · 2022

    Yoseftal hospital addition

  • $3.8M

    St Alexius Medical Center · Bismarck, ND · 2024

    Chi st. Alexius health ultrasound initiative

  • $3.7M

    New York University School of Medicine · New York, NY · 2023

    Tamale education and innovation center for health

  • $3.7M

    Central Montana Medical Facilities · Lewistown, MT · 2023

    Cancer center at central montana medical center

  • $3.7M

    T1d Exchange · Boston, MA · 2021

    Data approach to improve quality and outcomes for individuals with t1d

  • $3.7M

    Bhsh System · Grand Rapids, MI · 2022

    Study the feasibility of telerobotic heart attack and stroke interventions

  • $3.7M

    Helmholtz Zentrum Munchen (Gmbh) · 2021

    Identification of infants with high risk of t1d - primary prevention

  • $3.6M

    The Sheba Fund for Health Services and Research (Ra) · 2022

    The helmsley center for innovative surgical training

  • $3.5M

    Hillel Yaffe Medical Center · 2024

    Construction of pet-ct institute

  • $3.5M

    Maccabi Healthcare Services · 2021

    Da vinci 4xi system dual console surgical robot and sterilization equip.

  • $3.5M

    State of Nevada Department of Division of State Parks · Carson City, NV · 2024

    Valley of fire visitor center

  • $3.5M

    State of Nevada Department of Division of State Parks · Carson City, NV · 2023

    Ice age fossil state park trails and outdoor amenities

  • $3.5M

    State of Nevada Department of Division of State Parks · Carson City, NV · 2023

    Valley of fire visitor center

  • $3.5M

    Blue Circle Health · Wilmington, DE · 2022

    Development of blue circle health

  • $3.5M

    The Broad Institute · Cambridge, MA · 2024

    Novel therapeutic approaches for crohns disease

  • $3.5M

    Blue Circle Health · Wilmington, DE · 2023

    Development of blue circle health

  • $3.5M

    Indiana University · Indianapolis, IN · 2021

    Ampath model replication in ghana

  • $3.5M

    Central Montana Medical Facilities · Lewistown, MT · 2022

    Cancer center at central montana medical center

  • $3.3M

    Bar Ilan University in Israel · 2024

    The leona m. And harry b. Helmsley energy prototype lab at bar-ilan university

  • $3.3M

    New Venture Fund · Washington, DC · 2021

    Type 1 diabetes camps project (2022 - 2024)

  • $3.3M

    St Luke Health Care Foundation · West Chicago, IL · 2024

    Hope center for women and children

  • $3.2M

    Bar Ilan University · 2023

    The leona m. And harry b. Helmsley energy prototype lab at bar-ilan university

  • $3.2M

    Fairview Health Services · Minneapolis, MN · 2024

    Improving survival outcomes through university of minnesota medical center ecmo center of excellence

  • $3.2M

    Hillel Yaffe Medical Center · 2024

    Eye institute and ambulatory surgery center

  • $3.1M

    National Park Foundation · Washington, DC · 2022

    Little bighorn battlefield national monument visitor center

  • $3.1M

    World Health Organization · 2024

    Strengthening the capacity of the global diabetes compact

  • $3.1M

    World Health Organization · 2024

    Strengthening integrated prevention and control of chronic and severe ncds in the who african region, using t1d, scd, arf, and rhd as entry points

  • $3.1M

    Renown Health Foundation · Reno, NV · 2022

    Simulation and innovation center at renown health

  • $3.1M

    Clinton Health Access Initiative · Boston, MA · 2023

    Improving medical oxygen production and utilization

  • $3.0M

    Brigham and Women'S Hospital · Boston, MA · 2021

    Global partnership to achieve universal access for t1d and ncds

  • $3.0M

    St Luke Health Care Foundation · West Chicago, IL · 2023

    Hope center for women and children

  • $3.0M

    Trinity Health · Minot, ND · 2024

    Trinity health ultrasound initiative

  • $3.0M

    The Weizmann Institute of Science · 2024

    Early childhood development and community center at the weizmann institute of science

  • $3.0M

    Tel-Aviv University · 2023

    Helmsley medical simulation center

  • $3.0M

    The Weizmann Institute of Science · 2023

    Early childhood development and community center at the weizmann institute of science

  • $3.0M

    Diabetes Nsw · 2022

    Improvements in outcomes for young people with diabetes in less-resourced countries

  • $3.0M

    The Jewish Agency for Israel · 2022

    Flights for new immigrants from russia

  • $3.0M

    Avera McKennan Hospital and University Health Center · Sioux Falls, SD · 2021

    Avera behavioral health center expansion

  • $3.0M

    Jdrf T1d Fund Llc · Boston, MA · 2021

    Jdrf t1d fund phase iii

  • $3.0M

    South Dakota Parks & Wildlife Foundation · Pierre, SD · 2021

    Custer state park bison center

  • $3.0M

    The Broad Institute · Cambridge, MA · 2021

    Novel therapeutic approaches for crohns disease

  • $3.0M

    Children'S Mercy Hospital · Kansas City, MO · 2022

    Type 1 diabetes rapid learning lab

  • $3.0M

    Kmr Advancement of Medical Centers Ltd · 2021

    Establishment of the health discovery tower

  • $2.9M

    Helmholtz Zentrum Munchen (Gmbh) · 2023

    Continuation of the gppad-02-study: identification of infants with increased type 1 diabetes risk for enrollment into primary prevention trials

  • $2.9M

    Mass General Brigham for the Brigham and Women'S Hospital · Boston, MA · 2024

    Real-time post-op touchless, remote monitoring in crohns disease the sapphire trial

  • $2.9M

    Sanford · Fargo, ND · 2022

    Sanford health ultrasound project

  • $2.9M

    World Health Organization · 2023

    Strengthening integrated prevention and control of chronic and severe ncds in the who african region, using t1d, scd, arf, and rhd as entry points

  • $2.9M

    Jerusalem College of Technology · 2021

    Helmsley faculty of life and health sciences building

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Source: IRS Form 990-PF, Part XV, as filed by the foundation. These are grants already paid — a record of what this funder backs, not an open call.