Funding search · EIN 137184401 · New York, NY

The Leona M and Harry B Helmsley

A private foundation (files IRS Form 990-PF). Most private foundations do not take unsolicited applications; the route in is usually a program officer.

2,251
grants reported
$1.69B
total given
2021–2024
filing years
$393,039
median grant

Based on grants this organization reported to the IRS for tax years 20212024. This is what they filed, not a complete record of their giving, and recent years may be incomplete because filings lag.

What they fund

diseasecrohnshealthdiabetescentertypeultrasoundcare

Funder website ↗Full IRS filings ↗How this is builtReport an error

Funding pattern

What this funder pays for, at what size, and how to position adjacent work. Read from their filings, with every number checked against the record.

Where the money goes

  • Type 1 diabetes care, prevention trials, and global access
  • Crohn's disease mechanism, diagnostics, and therapeutic research
  • Rural US hospital equipment and capital, especially Upper Midwest and Hawaii
  • Israeli hospital construction and university science buildings
  • Sub-Saharan Africa health systems, WASH, and maternal-child care
  • Emergency and telehealth systems: stroke, ECMO, point-of-care ultrasound

Typical grant

Median grant is about $393,000, with the middle half between $156,000 and $927,000. The seven-figure checks go to two things: bricks and equipment (hospital wings in Israel, cancer centers in Hawaii, ultrasound fleets across North Dakota and Minnesota) and multi-year research or scale-up commitments in T1D and Crohn's, often $1.5M to $5M. Repeat giving is the norm, and the same recipient frequently appears two or three times in one year as a multi-payment award.

Their words

Phrases from their own grant descriptions, worth speaking back to them.

  • T1D
  • Crohn's disease
  • ultrasound initiative
  • scaling
  • quality improvement
  • access to primary care

Positioning adjacent work

  • Frame diabetes work as T1D specifically, tied to outcomes, registries, or quality improvement collaboratives.
  • For Crohn's, propose mechanistic or precision-diagnostic science with a defined trial or dataset endpoint.
  • Rural health proposals should name equipment, training, and geography: Dakotas, Minnesota, Montana, Hawaii.
  • Ask $1.5M to $3M multi-year for research; capital requests run $2M to $5M.

Worth knowing: Giving is concentrated in a small set of long-term partners (T1D Exchange, Blue Circle Health, Helmholtz Zentrum Munchen, Clalit, Billings Clinic, American Heart Association) and reads as relationship-driven and invited rather than competitive. Beyond the coastal research hubs in NY, MA, and CA, the money follows named geographies: rural Upper Midwest, Hawaii, Israel, and Ghana-centered Africa work.

200 grants matching “crohn · $134.1M

  • $3.5M

    The Broad Institute · Cambridge, MA · 2024

    Novel therapeutic approaches for crohns disease

  • $2.9M

    Mass General Brigham for the Brigham and Women'S Hospital · Boston, MA · 2024

    Real-time post-op touchless, remote monitoring in crohns disease the sapphire trial

  • $2.3M

    Icahn School of Medicine at Mount Sinai · New York City, NY · 2024

    Defining the pre-disease phase of crohns disease predict and prevent

  • $1.8M

    The Bionics Institute of Australia · 2024

    Patient-specific adaptive, electric therapy for crohns disease

  • $1.7M

    Mass General Brigham for the Massachusetts General Hospital · Boston, MA · 2024

    Microbes, molecules, and chemistry dysbiosis in crohns disease

  • $1.6M

    Crohn'S & Colitis Foundation · New York, NY · 2024

    Achieving remission in ibd optimizing treat-to-target in clinical practice

  • $1.5M

    Amsterdam Umc Research Bv · 2024

    A prospective randomized study of treatment selection based on epigenetic markers in crohns disease omicrohn

  • $1.5M

    The Chancellor Masters and Scholars of the University of Cambridge · 2024

    New insights into crohn's disease from studying naked mole rats

  • $1.5M

    Katholieke Universiteit Te Leuven · 2024

    Fat as a villain in crohn's disease.

  • $1.4M

    Mass General Brigham for the Massachusetts General Hospital · Boston, MA · 2024

    Validation of wireless thermal and microscopic imaging technology for quantifying inflammation and fibrosis in crohns disease

  • $1.2M

    Crohn'S & Colitis Foundation · New York, NY · 2024

    Ibd ventures academic incubator

  • $1.2M

    International Bowel Ultrasound Group Ev · 2024

    Development of an intestinal ultrasound score to evaluate inflammation and treatment response in crohns disease.

  • $1.1M

    Children'S Hospital Medical Center · Cincinnati, OH · 2024

    Artificial intelligence prediction of meaningful outcomes in newly diagnosed small bowel crohns disease

  • $1.1M

    The Regents of the University of California San Diego · La Jolla, CA · 2024

    The druggable gpcrome in crohns disease

  • $1.1M

    Regents of University of California Berkeley · Berkeley, CA · 2024

    Developing microbiome editing tools to advance understanding of the microbial influence on crohn's disease

  • $1.0M

    The Imperial College of Science Technology and Medicine · 2024

    Unraveling the immunopathology of perianal fistulizing crohns disease

  • $993,497

    Icahn School of Medicine at Mount Sinai · New York City, NY · 2024

    The use of glp-1r agonists to promote epithelial healing in crohns disease

  • $971,014

    The Broad Institute · Cambridge, MA · 2024

    Uncovering crohn's genetic risk in african-american and hispanic/latino populations

  • $920,802

    Icahn School of Medicine at Mount Sinai · New York City, NY · 2024

    Spatial mapping of fibromuscular crohns disease from genetic to senescent signals

  • $871,250

    Crohn'S Colitis Cure · 2024

    Enhancing inflammatory bowel disease care consumer-centric portal for better communication & reduced navigation stress

  • $863,618

    Cornell University for the Joan & Sanford I Weill Medical College · New York, NY · 2024

    Targeting the mycobiome in patients with crohns disease

  • $808,734

    The Chancellor Masters and Scholars of the University of Cambridge · 2024

    Does the western diet trigger crohn's disease via osmotic stress?

  • $756,699

    The Sheba Fund for Health Services and Research · 2024

    Israel ibd research nucleus (iirn) consortium capsule & omics for predicting exacerbation of crohns disease (core-cd)

  • $750,000

    Johns Hopkins University · Baltimore, MD · 2024

    Engineered cytokine/antibody fusion protein to treat crohns disease

  • $744,245

    Crohn'S & Colitis Foundation · New York, NY · 2024

    Accelerating enrollment in ibd clinical trials

  • $682,311

    The University of Edinburgh · 2024

    Mitochondrial damps as mechanistic biomarkers of mucosal inflammation in crohns disease (music)

  • $667,666

    Board of Trustees of the Leland Stanford Junior University · Stanford, CA · 2024

    Determining the therapeutic potential of statins on stricturing crohns disease

  • $618,257

    Icahn School of Medicine at Mount Sinai · New York City, NY · 2024

    Early life exposome biomarkers and crohn's disease risk the early-cd project

  • $612,471

    Chancellor Masters & Scholars of the University of Oxford · 2024

    Defining the signaling circuits and regulons mediating crohns fibrosis.

  • $599,035

    Yale University · New Haven, CT · 2024

    Targeting newly discovered host-microbiota interaction nodes to treat or prevent crohns disease

  • $583,881

    Icahn School of Medicine at Mount Sinai · New York City, NY · 2024

    Development of novel lrrk2 inhibitors to treat crohns disease

  • $583,113

    Children'S Hospital Medical Center · Cincinnati, OH · 2024

    Validation of a peripheral blood biomarker signature for anti-tnf response in patients with crohns disease (atpbios)

  • $523,716

    Icahn School of Medicine at Mount Sinai · New York City, NY · 2024

    Combination therapy of resilience intervention with biologics in crohns disease [catharsis trial]

  • $488,300

    Washington University · Saint Louis, MO · 2024

    Cellular biomarkers for pediatric crohns disease

  • $485,616

    Georgia Tech Research Corporation · Atlanta, GA · 2024

    Longitudinal tracking and reference-based interpretation of single-cell characteristics in treatment nave patients with crohns disease

  • $473,409

    University of Massachusetts Medical School · Worcester, MA · 2024

    Dieta anti-inflamatoria a crohns disease management strategy tailored for puerto ricans

  • $469,915

    Alimentiv · 2024

    Validation of the pro symptoms and impacts questionnaire for crohns disease

  • $467,726

    Crohn'S and Colitis UK · 2024

    Implementation of a lower gi diagnostic pathway in primary healthcare and development and dissemination of a lower gi patient toolkit

  • $463,512

    Clalit Health Services · 2024

    Israeli ibd research nucleus (iirn) consortium biomarker-based multidisciplinary team approach to improve early crohn's disease outcomes

  • $457,178

    The Regents of the University of Colorado Denver · Aurora, CO · 2024

    Epithelial mitochondrial dysfunction and extracellular vesicles in crohns disease fibrostenosis.

  • $429,646

    The Trustees of Columbia University in the City of New York · New York, NY · 2024

    Combinatorial perturbation of cellular network in crohns disease

  • $426,571

    Katholieke Universiteit Te Leuven · 2024

    Targeting chronic inflammation and tissue remodelling in crohn's disease with engineered t cells

  • $421,278

    Federal Institute of Technology Zurich Ethz · 2024

    Spatial biology of crohns colitis

  • $413,263

    The Trustees of Columbia University in the City of New York · New York, NY · 2024

    Combinatorial perturbation of cellular network in crohns disease

  • $413,016

    Yale University · New Haven, CT · 2024

    Exposomics for early life crohns disease

  • $402,672

    Genome Research Limited for the Wellcome Sanger Institute · 2024

    Scibd-response massive-scale single-cell rna-sequencing to identify transcriptomic predictors of response to biologic therapies in crohns disease

  • $394,365

    The Governors of the University of Calgary · 2024

    A drug-wide scan to identify repurposed medications for crohn's disease

  • $387,615

    The Cleveland Clinic Foundation · Cleveland, OH · 2024

    Mechanobiology of the intestinal epithelial barrier disruption in crohns disease

  • $384,292

    King'S College London · 2024

    Resolving harmful accumulation of innate lymphoid cells during crohns disease.

  • $374,912

    Crohn'S and Colitis Canada · 2024

    Implementation of nationwide telemedicine network to mitigate geographic disparities in access to healthcare for cd patients living in canada

  • $342,493

    Crohn'S & Colitis Foundation · New York, NY · 2024

    Application of machine learning to precision nutrition in crohns disease

  • $318,978

    Palo Alto Veterans Institute for Research · Palo Alto, CA · 2024

    Cell atlas of human intestinal lymphoid tissues and changes in crohn's disease

  • $315,421

    Australasian Gastro Intestinal Research Foundation Ltd · 2024

    Fecal microbiota transplantation (fmt) in crohn's disease the miro (microbiota restoration) study.

  • $310,748

    Crohn'S & Colitis Foundation · New York, NY · 2024

    International consortium on medical nutrition in ibd

  • $297,612

    Crohn'S and Colitis Canada · 2024

    Implementing a multimodal rct intervention to improve the transition of patients with crohns disease from pediatric to adult care

  • $237,102

    University of Pittsburgh · Pittsburgh, PA · 2024

    Single cell multimodal omics analysis of colonoscopic biopsy-derived immune cells in crohns disease

  • $235,000

    Crohn'S & Colitis Foundation · New York, NY · 2024

    Sponsorship for the 2025 crohns & colitis congress presented by the crohns & colitis foundation and the american gastroenterological association

  • $221,500

    Hebrew University of Jerusalem · 2024

    Methylation patterns of cell-free dna as a novel biomarker in crohns disease

  • $209,377

    Australasian Gastro Intestinal Research Foundation Ltd · 2024

    Fecal microbiota transplantation (fmt) in crohn's disease the miro (microbiota restoration) study.

  • $209,222

    The University of Edinburgh · 2024

    Human gut cell atlas - normal intestine and crohn's disease

  • $200,927

    University of Texas System for the University of Texas at Austin · Austin, TX · 2024

    Increasing access to crohns disease clinical care for the ibd center at ut health austin

  • $198,646

    University of Texas System for the University of Texas at Austin · Austin, TX · 2024

    Increasing access to crohns disease clinical care for the ibd center at ut health austin

  • $187,672

    Genome Research Limited for the Wellcome Sanger Institute · 2024

    Scibd-response massive-scale single-cell rna-sequencing to identify transcriptomic predictors of response to biologic therapies in crohns disease

  • $176,239

    University of Glasgow Court · 2024

    Combination therapy with biologics and partial enteral nutrition in adults with active ileocolonic crohns disease the biopic study

  • $149,796

    University of North Carolina at Chapel Hill · Chapel Hill, NC · 2024

    Genomic and microbial signatures predict post-operative crohns disease outcomes

  • $118,210

    The Sheba Fund for Health Services and Research · 2024

    The utility of hand-held ultrasound devices to detect bowel wall inflammatory activity in crohn's disease

  • $94,386

    Centre Hospitalier Regional De Nancy · 2024

    Prevention of extra-intestinal manifestations and comorbidities in crohns disease the nemo project

  • $92,033

    Regents of the University of Michigan · Ann Arbor, MI · 2024

    Evaluation of a gut-specific antifibrotic therapeutic in pre-clinical models of crohns disease

  • $47,977

    The University of Edinburgh · 2024

    Building a cross-discipline scientific approach towards understanding crohns disease - leveraging uk helmsley studies

  • $24,288

    St Mark'S Hospital Foundation · 2024

    Global perianal crohn's disease priority setting partnership

  • $1.7M

    Mass General Brigham for the Massachusetts General Hospital · Boston, MA · 2023

    Microbes, molecules, and chemistry: dysbiosis in crohns disease

  • $1.6M

    Icahn School of Medicine at Mount Sinai · New York City, NY · 2023

    Defining the pre-disease phase of crohns disease: predict and prevent

  • $1.6M

    Amc Medical Research Bv · 2023

    A prospective randomized study of treatment selection based on epigenetic markers in crohns disease: omicrohn

  • $1.5M

    The Broad Institute · Cambridge, MA · 2023

    Novel therapeutic approaches for crohns disease

  • $1.4M

    Children'S Hospital Medical Center · Cincinnati, OH · 2023

    Artificial intelligence prediction of meaningful outcomes in newly diagnosed small bowel crohns disease

  • $1.2M

    University of Glasgow Court · 2023

    Combination therapy with biologics and partial enteral nutrition in adults with active ileocolonic crohns disease: the biopic study

  • $1.2M

    Cambridge University Hospitals Nhs Foundation Trust · 2023

    The uk ibd bioresource: translating todays science into tomorrows treatments in crohns disease

  • $1.2M

    Regents of University of California Berkeley · Berkeley, CA · 2023

    Developing microbiome editing tools to advance understanding of the microbial influence on crohn's disease

  • $1.2M

    Rambam Health Corporation · 2023

    Microbial and dietary effects on immune composition and function in patients with crohn's

  • $1.2M

    Crohn'S & Colitis Foundation · New York, NY · 2023

    Ibd ventures academic incubator

  • $1.1M

    The University of Manchester · 2023

    A map of the intestine following regulatory t cell infusion into patients with active crohns disease at single-cell and spatial resolution

  • $1.1M

    Icahn School of Medicine at Mount Sinai · New York City, NY · 2023

    Spatial mapping of fibromuscular crohns disease: from genetic to senescent signals

  • $1.1M

    Crohn'S & Colitis Foundation · New York, NY · 2023

    Training awards program - class of 2021

  • $1.0M

    University of Cambridge · 2023

    Does biochemistry at the centre of life drive crohn's disease?

  • $1.0M

    Board of Trustees of the Leland Stanford Junior University · Stanford, CA · 2023

    Microbiome-based therapeutics for crohns disease

  • $988,042

    Regents of the University of Minnesota · Minneapolis, MN · 2023

    Standardized microbiota transplant therapy in crohns disease. Pilot trial.

  • $961,620

    The Weizmann Institute of Science · 2023

    Decoding the clinical impact of host and microbial intestinal proteomic landscape in crohns disease

  • $947,483

    The Weizmann Institute of Science · 2023

    Decoding personalized nutritional, microbiome and host patterns impacting clinical and prognostic features in crohns disease

  • $881,959

    University of Massachusetts Medical School · Worcester, MA · 2023

    Dieta anti-inflamatoria: a crohns disease management strategy tailored for puerto ricans

  • $836,979

    Board of Trustees of the Leland Stanford Junior University · Stanford, CA · 2023

    Investigating the role of the human exposome in crohns disease

  • $797,851

    Beth Israel Deaconess Medical Center · Boston, MA · 2023

    Proactive optimization of infliximab using a pharmacokinetic dashboard versus standard of care in patients with crohns disease: the optimize trial

  • $792,237

    Yale University · New Haven, CT · 2023

    Targeting newly discovered host-microbiota interaction nodes to treat or prevent crohns disease

  • $770,816

    Katholieke Universiteit Te Leuven · 2023

    Combination therapy of diet with biologicals for crohns disease: the oats study

  • $759,619

    Icahn School of Medicine at Mount Sinai · New York City, NY · 2023

    The melody trial: modulating early life microbiome through dietary intervention in crohn's disease

  • $752,326

    Mass General Brigham for the Massachusetts General Hospital · Boston, MA · 2023

    Wireless infrared imaging capsule for pinpointing inflammation in crohns disease

  • $713,088

    University of Cambridge · 2023

    Epigenetic regulation of intestinal epithelial mhc class 1 signalling - anovel mechanism in the pathogenesis of crohns disease

  • $712,850

    Crohn'S & Colitis Foundation · New York, NY · 2023

    Accelerating enrollment in ibd clinical trials

  • $705,894

    Mass General Brigham for the Massachusetts General Hospital · Boston, MA · 2023

    Crohn's disease in south asians: defining disease biology for prevention and better treatment

  • $704,764

    The Sheba Fund for Health Services and Research (Ra) · 2023

    Israel ibd research nucleus (iirn) consortium: capsule & omics for predicting exacerbation of crohns disease (core-cd)

  • $642,744

    Cork University Foundation · 2023

    Endoscopic multimodal assessment using advanced imaging integrated ai to predict recurrence in post-operative crohns disease - prospers

  • $595,677

    Crohn'S & Colitis Foundation · New York, NY · 2023

    Application of machine learning to precision nutrition in crohns disease

  • $588,266

    Crohn'S & Colitis Foundation · New York, NY · 2023

    Systematizing improvement interventions of urgent care management in crohns disease

  • $583,311

    University of Cambridge · 2023

    Does the western diet trigger crohn's disease via osmotic stress?

  • $581,625

    University of North Carolina at Chapel Hill · Chapel Hill, NC · 2023

    Genomic and microbial signatures predict post-operative crohns disease outcomes

  • $568,782

    Johns Hopkins University · Baltimore, MD · 2023

    Targeted, sustained release antifibrotic therapies for crohns disease patients

  • $562,426

    Crohn'S and Colitis Canada · 2023

    Implementation of nationwide telemedicine network to mitigate geographic disparities in access to healthcare for cd patients living in canada

  • $536,228

    Federal Institute of Technology Zurich Ethz · 2023

    Spatial biology of crohns colitis

  • $531,295

    King'S College London · 2023

    Identifying the role of food additive emulsifiers in crohn's disease: a randomized controlled trial

  • $499,459

    Mass General Brigham for the Brigham and Women'S Hospital · Boston, MA · 2023

    Investigation of anti-gm-csf autoantibodies as a disease determinant in crohns disease

  • $494,231

    The Scripps Research Institute · La Jolla, CA · 2023

    Translation of microbiota mechanisms on nod2 for crohns disease therapies

  • $485,617

    Georgia Tech Research Corporation · Atlanta, GA · 2023

    Longitudinal tracking and reference-based interpretation of single-cell characteristics in treatment nave patients with crohns disease

  • $480,848

    Georgia Tech Research Corporation · Atlanta, GA · 2023

    Longitudinal tracking and reference-based interpretation of single-cell characteristics in treatment nave patients with crohns disease

  • $452,465

    Clalit Health Services · 2023

    Israeli ibd research nucleus (iirn) consortium: biomarker-based multidisciplinary team approach to improve early crohn's disease outcomes

  • $447,521

    King'S College London · 2023

    Resolving harmful accumulation of innate lymphoid cells during crohns disease.

  • $444,246

    The University of Edinburgh · 2023

    Human gut cell atlas - normal intestine and crohn's disease

  • $429,712

    The Cleveland Clinic Foundation · Cleveland, OH · 2023

    Mechanobiology of the intestinal epithelial barrier disruption in crohns disease

  • $414,595

    Yale University · New Haven, CT · 2023

    Exposomics for early life crohns disease

  • $410,936

    Australasian Gastro Intestinal Research Foundation Ltd · 2023

    Fecal microbiota transplantation (fmt) in crohn's disease: the miro (microbiota restoration) study.

  • $404,688

    Icahn School of Medicine at Mount Sinai · New York City, NY · 2023

    Next phase of stem cell transplant for refractory crohns disease

  • $397,123

    Genome Research Limited for the Wellcome Sanger Institute · 2023

    Scibd-response: massive-scale single-cell rna-sequencing to identify transcriptomic predictors of response to biologic therapies in crohns disease

  • $374,591

    Children'S Hospital Corporation · Boston, MA · 2023

    Molecular and spatial single-cell remodeling in pediatric crohns disease

  • $369,880

    Regents of the University of Michigan · Ann Arbor, MI · 2023

    Using natural language processing of clinical documentation to improve personalization of care in crohn's disease

  • $367,129

    Aphp St Antoine Hospital · 2023

    Fecal microbiota transplantation in crohn's disease as relay after anti-tnf withdrawal (miracle)

  • $362,703

    Hebrew University of Jerusalem · 2023

    Methylation patterns of cell-free dna as a novel biomarker in crohns disease

  • $351,258

    The Trustees of Columbia University in the City of New York · New York, NY · 2023

    Combinatorial perturbation of cellular network in crohns disease

  • $338,970

    Washington University · Saint Louis, MO · 2023

    Cellular biomarkers for pediatric crohns disease

  • $334,798

    The Trustees of Columbia University in the City of New York · New York, NY · 2023

    Combinatorial perturbation of cellular network in crohns disease

  • $305,349

    Icahn School of Medicine at Mount Sinai · New York City, NY · 2023

    Next phase of stem cell transplant for refractory crohns disease

  • $298,606

    Yale University · New Haven, CT · 2023

    Exposomics for early life crohns disease

  • $293,370

    Trustees of the University of Pennsylvania · Philadelphia, PA · 2023

    The ultra processed western diet, the gut microbiome, and dietary xenobiotic exposure in crohns disease

  • $292,821

    Palo Alto Veterans Institute for Research · Palo Alto, CA · 2023

    Cell atlas of human intestinal lymphoid tissues and changes in crohn's disease

  • $290,049

    Vanderbilt University Medical Center · Nashville, TN · 2023

    Combinatorial single cell strategies for a crohn's disease gut cell atlas

  • $285,079

    Trustees of the University of Pennsylvania · Philadelphia, PA · 2023

    The ultra processed western diet, the gut microbiome, and dietary xenobiotic exposure in crohns disease

  • $284,646

    Crohn'S and Colitis Canada · 2023

    Implementing a multimodal rct intervention to improve the transition of patients with crohns disease from pediatric to adult care

  • $280,115

    University of Pittsburgh · Pittsburgh, PA · 2023

    Single cell multimodal omics analysis of colonoscopic biopsy-derived immune cells in crohns disease

  • $260,103

    University of North Carolina at Chapel Hill · Chapel Hill, NC · 2023

    Frequency and titer of granulocyte-macrophage colony-stimulating factor auto-antibodies in patients with crohn's-like disease of the pouch

  • $251,522

    Genome Research Limited for the Wellcome Sanger Institute · 2023

    Scibd-response: massive-scale single-cell rna-sequencing to identify transcriptomic predictors of response to biologic therapies in crohns disease

  • $247,654

    The Governors of the University of Calgary · 2023

    Quantitative proteomic profiling of fibrostenotic crohns disease patients

  • $243,196

    University of Pittsburgh · Pittsburgh, PA · 2023

    Single cell multimodal omics analysis of colonoscopic biopsy-derived immune cells in crohns disease

  • $221,420

    Chancellor Masters & Scholars of the University of Oxford · 2023

    Interrogating the mechanism of hypersensitivity to antibody-based drugs for development of a novel anti-tnf biologic for crohns disease

  • $212,881

    The University of Edinburgh · 2023

    Human gut cell atlas - normal intestine and crohn's disease

  • $200,000

    Crohn'S & Colitis Foundation · New York, NY · 2023

    Sponsorship for the 2024 crohns & colitis congress presented by the crohns & colitis foundation and the american gastroenterological association

  • $198,646

    University of Texas System for the University of Texas at Austin · Austin, TX · 2023

    Increasing access to crohns disease clinical care for the ibd center at ut health austin

  • $197,373

    Amc Medical Research Bv · 2023

    Development and validation of an epigenetic biomarker that predicts treatment success and allows personalized management in crohns disease

  • $196,411

    University of Texas System for the University of Texas at Austin · Austin, TX · 2023

    Increasing access to crohns disease clinical care for the ibd center at ut health austin

  • $195,494

    King'S College London · 2023

    Identifying the role of food additive emulsifiers in crohn's disease: a randomized controlled trial

  • $191,883

    The Governors of the University of Calgary · 2023

    The changing epidemiology and demographics of crohns disease in the western world over the next decade

  • $187,370

    Regents of the University of Michigan · Ann Arbor, MI · 2023

    Evaluation of a gut-specific antifibrotic therapeutic in pre-clinical models of crohns disease

  • $172,204

    The University of Edinburgh · 2023

    Mitochondrial damps as mechanistic biomarkers of mucosal inflammation in crohns disease (music)

  • $149,796

    University of North Carolina at Chapel Hill · Chapel Hill, NC · 2023

    Genomic and microbial signatures predict post-operative crohns disease outcomes

  • $142,264

    Regents of the University of Michigan · Ann Arbor, MI · 2023

    A system biology approach to understanding persistent symptoms in quiescent crohns disease

  • $121,036

    The Governors of the University of Calgary · 2023

    The changing epidemiology and demographics of crohns disease in the western world over the next decade

  • $115,418

    Crohn'S Colitis Cure · 2023

    Development of "cccare-p", a pediatric-specific crohns disease electronic medical record to drive care consistency and enhance transitions in care

  • $111,750

    The Cleveland Clinic Foundation · Cleveland, OH · 2023

    Development of an intestinal ultrasound index and a histopathology index for stricturing small bowel crohns disease

  • $106,296

    The University of Chicago · Chicago, IL · 2023

    Immuno-pharmacogenomics to understand and predict response to biologics in crohn's disease

  • $95,277

    Centre Hospitalier Regional De Nancy · 2023

    Prevention of extra-intestinal manifestations and comorbidities in crohns disease: the nemo project

  • $89,047

    The Governors of the University of Calgary · 2023

    Visualization of covid-19 vaccine serology in crohns disease: a knowledge translation strategy

  • $88,791

    Children'S Hospital Medical Center · Cincinnati, OH · 2023

    Precision crohns disease management utilizing predictive protein panels

  • $83,381

    Asian Health Care Foundation · 2023

    Improving access to diagnostics for crohn's disease patients living below the poverty line in southern india

  • $75,900

    Crohn'S and Colitis UK · 2023

    2021 & 2022 operating support for crohn's and colitis uk: knowledge and evidence personnel

  • $60,060

    Health Advocacy Summit · Greenwood, IN · 2023

    Crohns and colitis young adults network learning community, roundtable on adolescents and young adults with ibd

  • $60,000

    University College London · 2023

    Spit-c: using saliva to predict crohns disease

  • $1.5M

    The Broad Institute · Cambridge, MA · 2022

    Novel therapeutic approaches for crohns disease

  • $1.3M

    The Cleveland Clinic Foundation · Cleveland, OH · 2022

    Crohns fistulizing program investigator initiated clinical trials

  • $1.3M

    The Weizmann Institute of Science · 2022

    Decoding personalized nutritional, microbiome and host patterns impacting clinical and prognostic features in crohns disease

  • $1.3M

    The Regents of the University of California San Diego · La Jolla, CA · 2022

    The druggable gpcrome in crohns disease

  • $1.3M

    Klinikum Der Ludwig-Maximilians-Universitat Munchen · 2022

    Fecal microbiota transfer for maintenance of remission after induction treatment with exclusive enteral nutrition in crohns disease

  • $1.2M

    Brigham and Women'S Hospital · Boston, MA · 2022

    Investigation of anti-gm-csf autoantibodies as a disease determinant in crohns disease

  • $1.2M

    Crohn'S & Colitis Foundation · New York, NY · 2022

    Ibd ventures academic incubator

  • $1.2M

    The University of Manchester · 2022

    A map of the intestine following regulatory t cell infusion into patients with active crohns disease at single-cell and spatial resolution

  • $1.1M

    Crohn'S & Colitis Foundation · New York, NY · 2022

    Training awards program - class of 2021

  • $1.1M

    Ben-Gurion University of the Negev · 2022

    Cobmindex goes forward- a smartphone application for added psychological wellbeing in crohn's disease.

  • $1.0M

    New York University · New York, NY · 2022

    Identifying environmental contributors to crohn's disease

  • $1.0M

    Board of Trustees of the Leland Stanford Junior University · Stanford, CA · 2022

    Microbiome-based therapeutics for crohns disease

  • $997,937

    The Imperial College of Science Technology and Medicine · 2022

    Unraveling the immunopathology of perianal fistulizing crohns disease

  • $956,452

    The Broad Institute · Cambridge, MA · 2022

    Uncovering crohn's genetic risk in african-american and hispanic/latino populations

  • $955,956

    Cambridge University Hospitals Nhs Foundation Trust · 2022

    The uk ibd bioresource: translating todays science into tomorrows treatments in crohns disease

  • $954,604

    The Cleveland Clinic Foundation · Cleveland, OH · 2022

    Crohns fistulizing program investigator initiated clinical trials

  • $951,750

    Rambam Health Corporation · 2022

    Microbial and dietary effects on immune composition and function in patients with crohn's

  • $863,618

    Weill Medical College of Cornell University · New York, NY · 2022

    Targeting the mycobiome in patients with crohns disease

  • $843,986

    Massachusetts General Hospital · Boston, MA · 2022

    Wireless infrared imaging capsule for pinpointing inflammation in crohns disease

  • $798,066

    The Sheba Fund for Health Services and Research (Ra) · 2022

    Israel ibd research nucleus (iirn) consortium: capsule & omics for predicting exacerbation of crohns disease (core-cd)

  • $779,377

    International Bowel Ultrasound Group Ev · 2022

    Development of an intestinal ultrasound score to evaluate inflammation and treatment response in crohns disease.

  • $750,000

    Johns Hopkins University · Baltimore, MD · 2022

    Engineered cytokine/antibody fusion protein to treat crohns disease

  • $718,578

    International Bowel Ultrasound Group Ev · 2022

    Development of an intestinal ultrasound score to evaluate inflammation and treatment response in crohns disease.

  • $711,485

    University of Cambridge · 2022

    Epigenetic regulation of intestinal epithelial mhc class 1 signalling - a novel mechanism in the pathogenesis of crohns disease

  • $701,115

    The Weizmann Institute of Science · 2022

    Decoding the clinical impact of host and microbial intestinal proteomic landscape in crohns disease

  • $698,657

    Brigham and Women'S Hospital · Boston, MA · 2022

    Investigation of anti-gm-csf autoantibodies as a disease determinant in crohns disease

  • $690,953

    Board of Trustees of the Leland Stanford Junior University · Stanford, CA · 2022

    Investigating the role of the human exposome in crohns disease

  • $672,494

    University of Glasgow Court · 2022

    Combination therapy with biologics and partial enteral nutrition in adults with active ileocolonic crohns disease: the biopic study

  • $671,024

    Hebrew University of Jerusalem · 2022

    Methylation patterns of cell-free dna as a novel biomarker in crohns disease

  • $656,542

    Katholieke Universiteit Leuven · 2022

    Combination therapy of diet with biologicals for crohns disease: the oats study

  • $656,092

    Vanderbilt University Medical Center · Nashville, TN · 2022

    Combinatorial single cell strategies for a crohn's disease gut cell atlas

  • $618,790

    The University of Edinburgh · 2022

    Mitochondrial damps as mechanistic biomarkers of mucosal inflammation in crohns disease (music)

  • $599,718

    Clalit Health Services · 2022

    Biomarker-based multidisciplinary team (bio-mdt) approach to personalized microbial-targeted treatment of pouchitis and crohn's disease

  • $587,840

    Australasian Gastro Intestinal Research Foundation Ltd · 2022

    Fecal microbiota transplantation in crohn's disease: the miro study to improve health outcomes

  • $585,750

    University of North Carolina at Chapel Hill · Chapel Hill, NC · 2022

    Genomic and microbial signatures predict post-operative crohns disease outcomes

  • $570,831

    Crohn'S & Colitis Foundation · New York, NY · 2022

    Systematizing improvement interventions of urgent care management in crohns disease

  • $570,830

    Crohn'S & Colitis Foundation · New York, NY · 2022

    Systematizing improvement interventions of urgent care management in crohns disease

  • $562,008

    Johns Hopkins University · Baltimore, MD · 2022

    Targeted, sustained release antifibrotic therapies for crohns disease patients

Top recipients

Repeat recipients are the strongest signal of whether a funder has an open door or quietly re-funds the same organizations.

  • Helmholtz Zentrum Munchen (Gmbh)42 grants · $52.3M
  • Blue Circle Health11 grants · $45.4M
  • Shaare Zedek Medical Center22 grants · $42.6M
  • Clalit Health Services37 grants · $41.7M
  • American Heart Association20 grants · $30.7M
  • Regents of the University of Minnesota16 grants · $30.4M
  • The End Fund4 grants · $30.0M
  • The Regents of the University of Colorado Denver49 grants · $22.5M
  • Mass General Brigham for the Brigham and Women'S Hospital7 grants · $21.5M
  • Catholic Relief Services-Usccb13 grants · $21.4M

Giving over time

$382.7M
2021
$427.5M
2022
$440.0M
2023
$439.5M
2024

Grant history

The 100 largest of 2,251 grants.

  • $22.5M

    The End Fund · New York, NY · 2022

    Neglected tropical disease: reaching the last mile

  • $15.6M

    Blue Circle Health · Wilmington, DE · 2021

    Creation of blue circle health for underserved communities with t1d

  • $12.6M

    Regents of the University of Minnesota · Minneapolis, MN · 2021

    Minnesota first responder aed project

  • $9.9M

    Shaare Zedek Medical Center · 2021

    The helmsley cancer center at shaare zedek medical center jerusalem

  • $9.0M

    Mass General Brigham for the Brigham and Women'S Hospital · Boston, MA · 2023

    Pen-plus expansion

  • $7.0M

    Engineering Ministries International USA · Colorado Springs, CO · 2022

    Alaska wash project

  • $7.0M

    American Heart Association · Dallas, TX · 2024

    American heart association center for telehealth

  • $6.8M

    Mass General Brigham for the Brigham and Women'S Hospital · Boston, MA · 2024

    Accelerating progress and promoting quality t1d care for the poorest billion through the global pen-plus partnership

  • $6.7M

    Engineering Ministries International USA · Colorado Springs, CO · 2021

    Alaska wash project

  • $6.6M

    Nevada Department of Health and Human Services · Carson City, NV · 2022

    Nevada first responder aed project

  • $6.6M

    Geoscience Australia · 2022

    Digital earth africa - sustainable uptake and impact

  • $6.4M

    Commonwealth Healthcare Corporation · 2023

    Cnmi chcc mri/medical equipment upgrade project

  • $6.1M

    Yitzhak Shamir Medical Center · 2022

    Expansion and renovation of the cancer institute at shamir medical center

  • $5.8M

    Ben-Gurion University of the Negev · 2024

    Construction of the leona m. And harry b. Helmsley charitable trust computer science building

  • $5.7M

    Brigham and Women'S Hospital · Boston, MA · 2022

    Pen-plus expansion

  • $5.6M

    Nebraska Department of Health & Human Services · Lincoln, NE · 2021

    Nebraska first responder aed project

  • $5.4M

    Tzafon Medical Center · 2023

    The helmsley rehabilitation center of the north

  • $5.3M

    Iowa Department of Public Health · Des Moines, IA · 2021

    Iowa first responder aed initiative

  • $5.3M

    Hadassah Medical Organization · 2024

    Equipping the new hadassah - helmsley medical center, netivot

  • $5.3M

    Bridges To Prosperity · Denver, CO · 2021

    Transformative connectivity in rural ethiopia

  • $5.2M

    Shaare Zedek Medical Center · 2022

    The helmsley cancer center at shaare zedek medical center jerusalem

  • $5.2M

    Shaare Zedek Medical Center · 2023

    Linear accelerators for the radiotherapy institute

  • $5.1M

    The Baruch Padeh Medical Center Poriya · 2021

    The helmsley rehabilitation center of the north

  • $5.0M

    Regents of the University of Minnesota · Minneapolis, MN · 2022

    Redefining the future of emergency medicine

  • $5.0M

    Billings Clinic Foundation · Billings, MT · 2024

    Billings clinic surgical intensive care unit

  • $5.0M

    Kapiolani Health Foundation · Honolulu, HI · 2024

    Martha b. Smith cancer & infusion center at kapiolani medical center for women & children

  • $5.0M

    Stichting the Ocean Cleanup · 2024

    Develop and scale technologies to rid the oceans of plastics

  • $5.0M

    The Queens Medical Center · Honolulu, HI · 2024

    The queen's medical center - west oahu cancer center expansion

  • $5.0M

    Shaare Zedek Medical Center · 2023

    Development of the helmsley surgical wing

  • $5.0M

    Stichting the Ocean Cleanup · 2023

    Develop and scale technologies to rid the oceans of plastics

  • $5.0M

    Civica Foundation · Lehi, UT · 2021

    Affordable insulin biosimilars

  • $4.9M

    St Rose Dominican Health Foundation · Henderson, NV · 2023

    Dignity health - st. Rose dominican - siena campus ecmo program

  • $4.9M

    Fairview Health Services · Minneapolis, MN · 2023

    Improving survival outcomes through university of minnesota medical center ecmo center of excellence

  • $4.9M

    Regents of the University of Minnesota · Minneapolis, MN · 2023

    Minnesota first responder aed project

  • $4.9M

    Tel Aviv Sourasky Medical Center - Ichilov Hospital · 2024

    Construction of the sheltered -5 floor of the north tower

  • $4.5M

    Baptist Medical Centre · 2024

    Elevating maternal and pediatric healthcare

  • $4.5M

    Blue Circle Health · Wilmington, DE · 2024

    Development of blue circle health

  • $4.5M

    Blue Circle Health · Wilmington, DE · 2024

    Development of blue circle health

  • $4.5M

    The Baruch Padeh Medical Center Poriya · 2022

    The helmsley rehabilitation center of the north

  • $4.4M

    World Health Organization · 2022

    Strengthening the capacity of the global diabetes compact

  • $4.4M

    The Sheba Fund for Health Services and Research (Ra) · 2023

    The helmsley center for innovative surgical training

  • $4.2M

    Altru Health System · Grand Forks, ND · 2024

    Altru health system ultrasound initiative

  • $4.2M

    American Heart Association · Dallas, TX · 2023

    American heart association center for telehealth

  • $4.2M

    Jerusalem College of Technology · 2022

    Helmsley faculty of life and health sciences building

  • $4.1M

    The End Fund · New York, NY · 2023

    Reaching the last mile fund expansion

  • $4.1M

    Zefat Academic College · 2021

    Equipping zefat academic college's inst. For adv. Health training & ed.

  • $4.1M

    Clalit Health Services · 2022

    A new neonatal center for israels southern periphery at soroka medical center

  • $4.0M

    Holy Rosary Healthcare Foundation · Miles City, MT · 2022

    Holy rosary healthcare comprehensive cancer center

  • $4.0M

    Blue Circle Health · Wilmington, DE · 2024

    Development of blue circle health

  • $3.9M

    Wilcox Health Foundation · Lihue, HI · 2024

    Wilcox medical center equipment revitalization project

  • $3.9M

    Clalit Health Services · 2021

    Medical equipment for carmel medical center in haifa, israel

  • $3.9M

    Hadassah Medical Organization · 2022

    Creating and equipping a new comprehensive diagnostic and interventional imaging center

  • $3.8M

    Clalit Health Services · 2022

    Yoseftal hospital addition

  • $3.8M

    St Alexius Medical Center · Bismarck, ND · 2024

    Chi st. Alexius health ultrasound initiative

  • $3.7M

    New York University School of Medicine · New York, NY · 2023

    Tamale education and innovation center for health

  • $3.7M

    Central Montana Medical Facilities · Lewistown, MT · 2023

    Cancer center at central montana medical center

  • $3.7M

    T1d Exchange · Boston, MA · 2021

    Data approach to improve quality and outcomes for individuals with t1d

  • $3.7M

    Bhsh System · Grand Rapids, MI · 2022

    Study the feasibility of telerobotic heart attack and stroke interventions

  • $3.7M

    Helmholtz Zentrum Munchen (Gmbh) · 2021

    Identification of infants with high risk of t1d - primary prevention

  • $3.6M

    The Sheba Fund for Health Services and Research (Ra) · 2022

    The helmsley center for innovative surgical training

  • $3.5M

    Hillel Yaffe Medical Center · 2024

    Construction of pet-ct institute

  • $3.5M

    Maccabi Healthcare Services · 2021

    Da vinci 4xi system dual console surgical robot and sterilization equip.

  • $3.5M

    State of Nevada Department of Division of State Parks · Carson City, NV · 2024

    Valley of fire visitor center

  • $3.5M

    State of Nevada Department of Division of State Parks · Carson City, NV · 2023

    Ice age fossil state park trails and outdoor amenities

  • $3.5M

    State of Nevada Department of Division of State Parks · Carson City, NV · 2023

    Valley of fire visitor center

  • $3.5M

    Blue Circle Health · Wilmington, DE · 2022

    Development of blue circle health

  • $3.5M

    The Broad Institute · Cambridge, MA · 2024

    Novel therapeutic approaches for crohns disease

  • $3.5M

    Blue Circle Health · Wilmington, DE · 2023

    Development of blue circle health

  • $3.5M

    Indiana University · Indianapolis, IN · 2021

    Ampath model replication in ghana

  • $3.5M

    Central Montana Medical Facilities · Lewistown, MT · 2022

    Cancer center at central montana medical center

  • $3.3M

    Bar Ilan University in Israel · 2024

    The leona m. And harry b. Helmsley energy prototype lab at bar-ilan university

  • $3.3M

    New Venture Fund · Washington, DC · 2021

    Type 1 diabetes camps project (2022 - 2024)

  • $3.3M

    St Luke Health Care Foundation · West Chicago, IL · 2024

    Hope center for women and children

  • $3.2M

    Bar Ilan University · 2023

    The leona m. And harry b. Helmsley energy prototype lab at bar-ilan university

  • $3.2M

    Fairview Health Services · Minneapolis, MN · 2024

    Improving survival outcomes through university of minnesota medical center ecmo center of excellence

  • $3.2M

    Hillel Yaffe Medical Center · 2024

    Eye institute and ambulatory surgery center

  • $3.1M

    National Park Foundation · Washington, DC · 2022

    Little bighorn battlefield national monument visitor center

  • $3.1M

    World Health Organization · 2024

    Strengthening the capacity of the global diabetes compact

  • $3.1M

    World Health Organization · 2024

    Strengthening integrated prevention and control of chronic and severe ncds in the who african region, using t1d, scd, arf, and rhd as entry points

  • $3.1M

    Renown Health Foundation · Reno, NV · 2022

    Simulation and innovation center at renown health

  • $3.1M

    Clinton Health Access Initiative · Boston, MA · 2023

    Improving medical oxygen production and utilization

  • $3.0M

    Brigham and Women'S Hospital · Boston, MA · 2021

    Global partnership to achieve universal access for t1d and ncds

  • $3.0M

    St Luke Health Care Foundation · West Chicago, IL · 2023

    Hope center for women and children

  • $3.0M

    Trinity Health · Minot, ND · 2024

    Trinity health ultrasound initiative

  • $3.0M

    The Weizmann Institute of Science · 2024

    Early childhood development and community center at the weizmann institute of science

  • $3.0M

    Tel-Aviv University · 2023

    Helmsley medical simulation center

  • $3.0M

    The Weizmann Institute of Science · 2023

    Early childhood development and community center at the weizmann institute of science

  • $3.0M

    Diabetes Nsw · 2022

    Improvements in outcomes for young people with diabetes in less-resourced countries

  • $3.0M

    The Jewish Agency for Israel · 2022

    Flights for new immigrants from russia

  • $3.0M

    Avera McKennan Hospital and University Health Center · Sioux Falls, SD · 2021

    Avera behavioral health center expansion

  • $3.0M

    Jdrf T1d Fund Llc · Boston, MA · 2021

    Jdrf t1d fund phase iii

  • $3.0M

    South Dakota Parks & Wildlife Foundation · Pierre, SD · 2021

    Custer state park bison center

  • $3.0M

    The Broad Institute · Cambridge, MA · 2021

    Novel therapeutic approaches for crohns disease

  • $3.0M

    Children'S Mercy Hospital · Kansas City, MO · 2022

    Type 1 diabetes rapid learning lab

  • $3.0M

    Kmr Advancement of Medical Centers Ltd · 2021

    Establishment of the health discovery tower

  • $2.9M

    Helmholtz Zentrum Munchen (Gmbh) · 2023

    Continuation of the gppad-02-study: identification of infants with increased type 1 diabetes risk for enrollment into primary prevention trials

  • $2.9M

    Mass General Brigham for the Brigham and Women'S Hospital · Boston, MA · 2024

    Real-time post-op touchless, remote monitoring in crohns disease the sapphire trial

  • $2.9M

    Sanford · Fargo, ND · 2022

    Sanford health ultrasound project

  • $2.9M

    World Health Organization · 2023

    Strengthening integrated prevention and control of chronic and severe ncds in the who african region, using t1d, scd, arf, and rhd as entry points

  • $2.9M

    Jerusalem College of Technology · 2021

    Helmsley faculty of life and health sciences building

View all 2,251 grants →

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Source: IRS Form 990-PF, Part XV, as filed by the foundation. These are grants already paid — a record of what this funder backs, not an open call.