Funding search · EIN 137184401 · New York, NY

The Leona M and Harry B Helmsley

Name: The Leona M and Harry B Helmsley grants, 2021–2024
Creator: PaperOrbit
License: https://www.irs.gov/charities-non-profits/exempt-organization-public-disclosure-and-availability-requirements

A private foundation (files IRS Form 990-PF). Most private foundations do not take unsolicited applications; the route in is usually a program officer.

2,251
grants reported: $1.69B
total given: 2021–2024
filing years: $393,039
median grant

Based on grants this organization reported to the IRS for tax years 2021–2024. This is what they filed, not a complete record of their giving, and recent years may be incomplete because filings lag.

What they fund

disease crohns health diabetes center type ultrasound care

Funder website ↗Full IRS filings ↗How this is built Report an error

Funding pattern

What this funder pays for, at what size, and how to position adjacent work. Read from their filings, with every number checked against the record.

Where the money goes

Type 1 diabetes care, prevention trials, and global access
Crohn's disease mechanism, diagnostics, and therapeutic research
Rural US hospital equipment and capital, especially Upper Midwest and Hawaii
Israeli hospital construction and university science buildings
Sub-Saharan Africa health systems, WASH, and maternal-child care
Emergency and telehealth systems: stroke, ECMO, point-of-care ultrasound

Typical grant

Median grant is about $393,000, with the middle half between $156,000 and $927,000. The seven-figure checks go to two things: bricks and equipment (hospital wings in Israel, cancer centers in Hawaii, ultrasound fleets across North Dakota and Minnesota) and multi-year research or scale-up commitments in T1D and Crohn's, often $1.5M to $5M. Repeat giving is the norm, and the same recipient frequently appears two or three times in one year as a multi-payment award.

Their words

Phrases from their own grant descriptions, worth speaking back to them.

“T1D”
“Crohn's disease”
“ultrasound initiative”
“scaling”
“quality improvement”
“access to primary care”

Positioning adjacent work

Frame diabetes work as T1D specifically, tied to outcomes, registries, or quality improvement collaboratives.
For Crohn's, propose mechanistic or precision-diagnostic science with a defined trial or dataset endpoint.
Rural health proposals should name equipment, training, and geography: Dakotas, Minnesota, Montana, Hawaii.
Ask $1.5M to $3M multi-year for research; capital requests run $2M to $5M.

Worth knowing: Giving is concentrated in a small set of long-term partners (T1D Exchange, Blue Circle Health, Helmholtz Zentrum Munchen, Clalit, Billings Clinic, American Heart Association) and reads as relationship-driven and invited rather than competitive. Beyond the coastal research hubs in NY, MA, and CA, the money follows named geographies: rural Upper Midwest, Hawaii, Israel, and Ghana-centered Africa work.

42 grants matching “novel” · $31.5M

$3.5M
The Broad Institute · Cambridge, MA · 2024
Novel therapeutic approaches for crohns disease
$1.5M
Clalit Health Services · 2024
Clinical trial to evaluate a novel mdi-bgm decision support system
$1.3M
Children'S Hospital Corporation · Boston, MA · 2024
Advancing the development of a novel implantable glucose responsive glucagon (grg) delivery system
$732,284
Children'S Hospital Corporation · Boston, MA · 2024
Novel glucose binders for the development of glucose responsive insulin (gri)
$705,510
University of Notre Dame Du Lac · Notre Dame, ID · 2024
Development of a novel glucose-responsive glucagon delivery system
$583,881
Icahn School of Medicine at Mount Sinai · New York City, NY · 2024
Development of novel lrrk2 inhibitors to treat crohns disease
$275,861
Duke University · Durham, NC · 2024
Novel assays for proglucagon peptides to understand alpha cell function in health and diabetes
$221,500
Hebrew University of Jerusalem · 2024
Methylation patterns of cell-free dna as a novel biomarker in crohns disease
$41,318
Oregon Health & Science University · Portland, OR · 2024
Dissemination pilot the implementation of novel interventions in children's healthcare (nich) in another healthcare system
$1.5M
The Broad Institute · Cambridge, MA · 2023
Novel therapeutic approaches for crohns disease
$1.3M
Children'S Hospital Corporation · Boston, MA · 2023
Development of novel glucose responsive glucagon (grg) delivery system for the prevention of hypoglycemia for people with t1d
$1.1M
Children'S Hospital Corporation · Boston, MA · 2023
Development of novel glucose responsive glucagon (grg) delivery system for the prevention of hypoglycemia for people with t1d
$880,551
University of Melbourne · 2023
Animal and clinical evaluation of a novel continuous ketone sensor
$666,216
Children'S Hospital Corporation · Boston, MA · 2023
Novel glucose binders for the development of glucose responsive insulin (gri)
$665,654
Children'S Hospital Corporation · Boston, MA · 2023
Novel glucose binders for the development of glucose responsive insulin (gri)
$418,217
Clalit Health Services · 2023
Clinical trial to evaluate a novel mdi-bgm decision support system
$362,703
Hebrew University of Jerusalem · 2023
Methylation patterns of cell-free dna as a novel biomarker in crohns disease
$221,420
Chancellor Masters & Scholars of the University of Oxford · 2023
Interrogating the mechanism of hypersensitivity to antibody-based drugs for development of a novel anti-tnf biologic for crohns disease
$143,127
University of Notre Dame Du Lac · Notre Dame, IN · 2023
Development of a novel glucose-responsive glucagon delivery system
$1.5M
The Broad Institute · Cambridge, MA · 2022
Novel therapeutic approaches for crohns disease
$1.1M
Mayo Clinic · Rochester, MN · 2022
Development and evaluation of a novel algorithm for aid control for pregnant women with t1d
$1.0M
Clalit Health Services · 2022
Clinical trial to evaluate a novel mdi-bgm decision support system
$731,837
Adventist Health Systemsunbelt · Orlando, FL · 2022
Determining whether a novel class of drugs might prevent hypoglycemia in t1d patients
$711,485
University of Cambridge · 2022
Epigenetic regulation of intestinal epithelial mhc class 1 signalling - a novel mechanism in the pathogenesis of crohns disease
$671,024
Hebrew University of Jerusalem · 2022
Methylation patterns of cell-free dna as a novel biomarker in crohns disease
$406,254
Clalit Health Services · 2022
Clinical trial to evaluate a novel mdi-bgm decision support system
$397,048
University of Notre Dame Du Lac · Notre Dame, IN · 2022
Development of a novel glucose-responsive glucagon delivery system
$159,416
Chancellor Masters & Scholars of the University of Oxford · 2022
Interrogating the mechanism of hypersensitivity to antibody-based drugs for development of a novel anti-tnf biologic for crohns disease
$3.0M
The Broad Institute · Cambridge, MA · 2021
Novel therapeutic approaches for crohns disease
$1.2M
Children'S Hospital Corporation · Boston, MA · 2021
Development of novel glucose responsive glucagon (grg) delivery system
$775,164
Hebrew University of Jerusalem · 2021
Methylation patterns of cell-free dna as a novel biomarker in crohns
$662,214
Children'S Hospital Corporation · Boston, MA · 2021
Novel glucose binders for the development of glucose responsive insulins
$589,062
Clalit Health Services · 2021
Clinical trial to evaluate a novel mdi-bgm decision support system
$581,100
University of Notre Dame Du Lac · Notre Dame, IN · 2021
Development of a novel glucose-responsive glucagon delivery system
$552,076
University of Melbourne · 2021
Animal and clinical evaluation of a novel continuous ketone sensor
$432,631
Jdrf International · New York, NY · 2021
Development of novel insulin infusion set
$260,774
Saint Louis University · Saint Louis, MO · 2021
Novel target to fight alpha cell dysfunction & stop hypoglycemia in t1d
$249,301
Hebrew University of Jerusalem · 2021
Methylation patterns of cell-free dna as a novel biomarker in crohns
$210,228
Columbia University · New York, NY · 2021
Novel spatially resolved genomic profiling of crohns disease tissue
$200,000
Region Hovedstaden · 2021
Identification/screening of novel glucagonotropic alpha-cell receptors
$146,811
Columbia University · New York, NY · 2021
Novel spatially resolved genomic profiling of crohns disease tissue
$18,350
Hebrew University of Jerusalem · 2021
Methylation patterns of cell-free dna as a novel biomarker in crohns

Top recipients

Repeat recipients are the strongest signal of whether a funder has an open door or quietly re-funds the same organizations.

Helmholtz Zentrum Munchen (Gmbh)42 grants · $52.3M
Blue Circle Health11 grants · $45.4M
Shaare Zedek Medical Center22 grants · $42.6M
Clalit Health Services37 grants · $41.7M
American Heart Association20 grants · $30.7M
Regents of the University of Minnesota16 grants · $30.4M
The End Fund4 grants · $30.0M
The Regents of the University of Colorado Denver49 grants · $22.5M
Mass General Brigham for the Brigham and Women'S Hospital7 grants · $21.5M
Catholic Relief Services-Usccb13 grants · $21.4M

Giving over time

$382.7M

2021

$427.5M

2022

$440.0M

2023

$439.5M

2024

Grant history

The 100 largest of 2,251 grants.

$22.5M
The End Fund · New York, NY · 2022
Neglected tropical disease: reaching the last mile
$15.6M
Blue Circle Health · Wilmington, DE · 2021
Creation of blue circle health for underserved communities with t1d
$12.6M
Regents of the University of Minnesota · Minneapolis, MN · 2021
Minnesota first responder aed project
$9.9M
Shaare Zedek Medical Center · 2021
The helmsley cancer center at shaare zedek medical center jerusalem
$9.0M
Mass General Brigham for the Brigham and Women'S Hospital · Boston, MA · 2023
Pen-plus expansion
$7.0M
Engineering Ministries International USA · Colorado Springs, CO · 2022
Alaska wash project
$7.0M
American Heart Association · Dallas, TX · 2024
American heart association center for telehealth
$6.8M
Mass General Brigham for the Brigham and Women'S Hospital · Boston, MA · 2024
Accelerating progress and promoting quality t1d care for the poorest billion through the global pen-plus partnership
$6.7M
Engineering Ministries International USA · Colorado Springs, CO · 2021
Alaska wash project
$6.6M
Nevada Department of Health and Human Services · Carson City, NV · 2022
Nevada first responder aed project
$6.6M
Geoscience Australia · 2022
Digital earth africa - sustainable uptake and impact
$6.4M
Commonwealth Healthcare Corporation · 2023
Cnmi chcc mri/medical equipment upgrade project
$6.1M
Yitzhak Shamir Medical Center · 2022
Expansion and renovation of the cancer institute at shamir medical center
$5.8M
Ben-Gurion University of the Negev · 2024
Construction of the leona m. And harry b. Helmsley charitable trust computer science building
$5.7M
Brigham and Women'S Hospital · Boston, MA · 2022
Pen-plus expansion
$5.6M
Nebraska Department of Health & Human Services · Lincoln, NE · 2021
Nebraska first responder aed project
$5.4M
Tzafon Medical Center · 2023
The helmsley rehabilitation center of the north
$5.3M
Iowa Department of Public Health · Des Moines, IA · 2021
Iowa first responder aed initiative
$5.3M
Hadassah Medical Organization · 2024
Equipping the new hadassah - helmsley medical center, netivot
$5.3M
Bridges To Prosperity · Denver, CO · 2021
Transformative connectivity in rural ethiopia
$5.2M
Shaare Zedek Medical Center · 2022
The helmsley cancer center at shaare zedek medical center jerusalem
$5.2M
Shaare Zedek Medical Center · 2023
Linear accelerators for the radiotherapy institute
$5.1M
The Baruch Padeh Medical Center Poriya · 2021
The helmsley rehabilitation center of the north
$5.0M
Regents of the University of Minnesota · Minneapolis, MN · 2022
Redefining the future of emergency medicine
$5.0M
Billings Clinic Foundation · Billings, MT · 2024
Billings clinic surgical intensive care unit
$5.0M
Kapiolani Health Foundation · Honolulu, HI · 2024
Martha b. Smith cancer & infusion center at kapiolani medical center for women & children
$5.0M
Stichting the Ocean Cleanup · 2024
Develop and scale technologies to rid the oceans of plastics
$5.0M
The Queens Medical Center · Honolulu, HI · 2024
The queen's medical center - west oahu cancer center expansion
$5.0M
Shaare Zedek Medical Center · 2023
Development of the helmsley surgical wing
$5.0M
Stichting the Ocean Cleanup · 2023
Develop and scale technologies to rid the oceans of plastics
$5.0M
Civica Foundation · Lehi, UT · 2021
Affordable insulin biosimilars
$4.9M
St Rose Dominican Health Foundation · Henderson, NV · 2023
Dignity health - st. Rose dominican - siena campus ecmo program
$4.9M
Fairview Health Services · Minneapolis, MN · 2023
Improving survival outcomes through university of minnesota medical center ecmo center of excellence
$4.9M
Regents of the University of Minnesota · Minneapolis, MN · 2023
Minnesota first responder aed project
$4.9M
Tel Aviv Sourasky Medical Center - Ichilov Hospital · 2024
Construction of the sheltered -5 floor of the north tower
$4.5M
Baptist Medical Centre · 2024
Elevating maternal and pediatric healthcare
$4.5M
Blue Circle Health · Wilmington, DE · 2024
Development of blue circle health
$4.5M
Blue Circle Health · Wilmington, DE · 2024
Development of blue circle health
$4.5M
The Baruch Padeh Medical Center Poriya · 2022
The helmsley rehabilitation center of the north
$4.4M
World Health Organization · 2022
Strengthening the capacity of the global diabetes compact
$4.4M
The Sheba Fund for Health Services and Research (Ra) · 2023
The helmsley center for innovative surgical training
$4.2M
Altru Health System · Grand Forks, ND · 2024
Altru health system ultrasound initiative
$4.2M
American Heart Association · Dallas, TX · 2023
American heart association center for telehealth
$4.2M
Jerusalem College of Technology · 2022
Helmsley faculty of life and health sciences building
$4.1M
The End Fund · New York, NY · 2023
Reaching the last mile fund expansion
$4.1M
Zefat Academic College · 2021
Equipping zefat academic college's inst. For adv. Health training & ed.
$4.1M
Clalit Health Services · 2022
A new neonatal center for israels southern periphery at soroka medical center
$4.0M
Holy Rosary Healthcare Foundation · Miles City, MT · 2022
Holy rosary healthcare comprehensive cancer center
$4.0M
Blue Circle Health · Wilmington, DE · 2024
Development of blue circle health
$3.9M
Wilcox Health Foundation · Lihue, HI · 2024
Wilcox medical center equipment revitalization project
$3.9M
Clalit Health Services · 2021
Medical equipment for carmel medical center in haifa, israel
$3.9M
Hadassah Medical Organization · 2022
Creating and equipping a new comprehensive diagnostic and interventional imaging center
$3.8M
Clalit Health Services · 2022
Yoseftal hospital addition
$3.8M
St Alexius Medical Center · Bismarck, ND · 2024
Chi st. Alexius health ultrasound initiative
$3.7M
New York University School of Medicine · New York, NY · 2023
Tamale education and innovation center for health
$3.7M
Central Montana Medical Facilities · Lewistown, MT · 2023
Cancer center at central montana medical center
$3.7M
T1d Exchange · Boston, MA · 2021
Data approach to improve quality and outcomes for individuals with t1d
$3.7M
Bhsh System · Grand Rapids, MI · 2022
Study the feasibility of telerobotic heart attack and stroke interventions
$3.7M
Helmholtz Zentrum Munchen (Gmbh) · 2021
Identification of infants with high risk of t1d - primary prevention
$3.6M
The Sheba Fund for Health Services and Research (Ra) · 2022
The helmsley center for innovative surgical training
$3.5M
Hillel Yaffe Medical Center · 2024
Construction of pet-ct institute
$3.5M
Maccabi Healthcare Services · 2021
Da vinci 4xi system dual console surgical robot and sterilization equip.
$3.5M
State of Nevada Department of Division of State Parks · Carson City, NV · 2024
Valley of fire visitor center
$3.5M
State of Nevada Department of Division of State Parks · Carson City, NV · 2023
Ice age fossil state park trails and outdoor amenities
$3.5M
State of Nevada Department of Division of State Parks · Carson City, NV · 2023
Valley of fire visitor center
$3.5M
Blue Circle Health · Wilmington, DE · 2022
Development of blue circle health
$3.5M
The Broad Institute · Cambridge, MA · 2024
Novel therapeutic approaches for crohns disease
$3.5M
Blue Circle Health · Wilmington, DE · 2023
Development of blue circle health
$3.5M
Indiana University · Indianapolis, IN · 2021
Ampath model replication in ghana
$3.5M
Central Montana Medical Facilities · Lewistown, MT · 2022
Cancer center at central montana medical center
$3.3M
Bar Ilan University in Israel · 2024
The leona m. And harry b. Helmsley energy prototype lab at bar-ilan university
$3.3M
New Venture Fund · Washington, DC · 2021
Type 1 diabetes camps project (2022 - 2024)
$3.3M
St Luke Health Care Foundation · West Chicago, IL · 2024
Hope center for women and children
$3.2M
Bar Ilan University · 2023
The leona m. And harry b. Helmsley energy prototype lab at bar-ilan university
$3.2M
Fairview Health Services · Minneapolis, MN · 2024
Improving survival outcomes through university of minnesota medical center ecmo center of excellence
$3.2M
Hillel Yaffe Medical Center · 2024
Eye institute and ambulatory surgery center
$3.1M
National Park Foundation · Washington, DC · 2022
Little bighorn battlefield national monument visitor center
$3.1M
World Health Organization · 2024
Strengthening the capacity of the global diabetes compact
$3.1M
World Health Organization · 2024
Strengthening integrated prevention and control of chronic and severe ncds in the who african region, using t1d, scd, arf, and rhd as entry points
$3.1M
Renown Health Foundation · Reno, NV · 2022
Simulation and innovation center at renown health
$3.1M
Clinton Health Access Initiative · Boston, MA · 2023
Improving medical oxygen production and utilization
$3.0M
Brigham and Women'S Hospital · Boston, MA · 2021
Global partnership to achieve universal access for t1d and ncds
$3.0M
St Luke Health Care Foundation · West Chicago, IL · 2023
Hope center for women and children
$3.0M
Trinity Health · Minot, ND · 2024
Trinity health ultrasound initiative
$3.0M
The Weizmann Institute of Science · 2024
Early childhood development and community center at the weizmann institute of science
$3.0M
Tel-Aviv University · 2023
Helmsley medical simulation center
$3.0M
The Weizmann Institute of Science · 2023
Early childhood development and community center at the weizmann institute of science
$3.0M
Diabetes Nsw · 2022
Improvements in outcomes for young people with diabetes in less-resourced countries
$3.0M
The Jewish Agency for Israel · 2022
Flights for new immigrants from russia
$3.0M
Avera McKennan Hospital and University Health Center · Sioux Falls, SD · 2021
Avera behavioral health center expansion
$3.0M
Jdrf T1d Fund Llc · Boston, MA · 2021
Jdrf t1d fund phase iii
$3.0M
South Dakota Parks & Wildlife Foundation · Pierre, SD · 2021
Custer state park bison center
$3.0M
The Broad Institute · Cambridge, MA · 2021
Novel therapeutic approaches for crohns disease
$3.0M
Children'S Mercy Hospital · Kansas City, MO · 2022
Type 1 diabetes rapid learning lab
$3.0M
Kmr Advancement of Medical Centers Ltd · 2021
Establishment of the health discovery tower
$2.9M
Helmholtz Zentrum Munchen (Gmbh) · 2023
Continuation of the gppad-02-study: identification of infants with increased type 1 diabetes risk for enrollment into primary prevention trials
$2.9M
Mass General Brigham for the Brigham and Women'S Hospital · Boston, MA · 2024
Real-time post-op touchless, remote monitoring in crohns disease the sapphire trial
$2.9M
Sanford · Fargo, ND · 2022
Sanford health ultrasound project
$2.9M
World Health Organization · 2023
Strengthening integrated prevention and control of chronic and severe ncds in the who african region, using t1d, scd, arf, and rhd as entry points
$2.9M
Jerusalem College of Technology · 2021
Helmsley faculty of life and health sciences building

View all 2,251 grants →

Grants already paid are the record; PaperOrbit reads your paper and finds the funders whose record matches it — then explains why.

Search funders like this one

Source: IRS Form 990-PF, Part XV, as filed by the foundation. These are grants already paid — a record of what this funder backs, not an open call.