Funding search · EIN 137184401 · New York, NY

The Leona M and Harry B Helmsley

Name: The Leona M and Harry B Helmsley grants, 2021–2024
Creator: PaperOrbit
License: https://www.irs.gov/charities-non-profits/exempt-organization-public-disclosure-and-availability-requirements

A private foundation (files IRS Form 990-PF). Most private foundations do not take unsolicited applications; the route in is usually a program officer.

2,251
grants reported: $1.69B
total given: 2021–2024
filing years: $393,039
median grant

Based on grants this organization reported to the IRS for tax years 2021–2024. This is what they filed, not a complete record of their giving, and recent years may be incomplete because filings lag.

What they fund

disease crohns health diabetes center type ultrasound care

Funder website ↗Full IRS filings ↗How this is built Report an error

Funding pattern

What this funder pays for, at what size, and how to position adjacent work. Read from their filings, with every number checked against the record.

Where the money goes

Type 1 diabetes care, prevention trials, and global access
Crohn's disease mechanism, diagnostics, and therapeutic research
Rural US hospital equipment and capital, especially Upper Midwest and Hawaii
Israeli hospital construction and university science buildings
Sub-Saharan Africa health systems, WASH, and maternal-child care
Emergency and telehealth systems: stroke, ECMO, point-of-care ultrasound

Typical grant

Median grant is about $393,000, with the middle half between $156,000 and $927,000. The seven-figure checks go to two things: bricks and equipment (hospital wings in Israel, cancer centers in Hawaii, ultrasound fleets across North Dakota and Minnesota) and multi-year research or scale-up commitments in T1D and Crohn's, often $1.5M to $5M. Repeat giving is the norm, and the same recipient frequently appears two or three times in one year as a multi-payment award.

Their words

Phrases from their own grant descriptions, worth speaking back to them.

“T1D”
“Crohn's disease”
“ultrasound initiative”
“scaling”
“quality improvement”
“access to primary care”

Positioning adjacent work

Frame diabetes work as T1D specifically, tied to outcomes, registries, or quality improvement collaboratives.
For Crohn's, propose mechanistic or precision-diagnostic science with a defined trial or dataset endpoint.
Rural health proposals should name equipment, training, and geography: Dakotas, Minnesota, Montana, Hawaii.
Ask $1.5M to $3M multi-year for research; capital requests run $2M to $5M.

Worth knowing: Giving is concentrated in a small set of long-term partners (T1D Exchange, Blue Circle Health, Helmholtz Zentrum Munchen, Clalit, Billings Clinic, American Heart Association) and reads as relationship-driven and invited rather than competitive. Beyond the coastal research hubs in NY, MA, and CA, the money follows named geographies: rural Upper Midwest, Hawaii, Israel, and Ghana-centered Africa work.

67 grants matching “therapies” · $37.9M

$1.8M
The Bionics Institute of Australia · 2024
Patient-specific adaptive, electric therapy for crohns disease
$1.5M
Children'S Hospital Corporation · Boston, MA · 2024
Very early onset inflammatory bowel disease (veoibd) precision molecular diagnoses to targeted therapies boston studies
$1.3M
The Cleveland Clinic Foundation · Cleveland, OH · 2024
Development of a next-generation biomarker tool to accelerate the development of effective anti-fibrotic therapies
$667,252
Care-for-Rare Foundation · 2024
Very early onset inflammatory bowel disease (veoibd) precision molecular diagnoses to targeted therapies munich studies
$609,141
Seattle Children'S Hospital · Seattle, WA · 2024
Expanding use of engineered tregs in t1d therapy (phase 4)
$555,480
The Hospital for Sick Children · 2024
Very early onset inflammatory bowel disease (veoibd) precision molecular diagnoses to targeted therapies-toronto studies
$523,716
Icahn School of Medicine at Mount Sinai · New York City, NY · 2024
Combination therapy of resilience intervention with biologics in crohns disease [catharsis trial]
$402,672
Genome Research Limited for the Wellcome Sanger Institute · 2024
Scibd-response massive-scale single-cell rna-sequencing to identify transcriptomic predictors of response to biologic therapies in crohns disease
$259,951
Alimentiv · 2024
Development of a next generation biomarker tool to accelerate the development of effective anti-fibrotic therapies
$220,000
Icahn School of Medicine at Mount Sinai · New York City, NY · 2024
Very early onset inflammatory bowel disease (veoibd) precision molecular diagnoses to targeted therapies mount sinai studies
$211,718
Cardiff University · 2024
T1d-plus an adaptive trial platform for the study of combination therapies in new-onset t1d
$187,672
Genome Research Limited for the Wellcome Sanger Institute · 2024
Scibd-response massive-scale single-cell rna-sequencing to identify transcriptomic predictors of response to biologic therapies in crohns disease
$176,239
University of Glasgow Court · 2024
Combination therapy with biologics and partial enteral nutrition in adults with active ileocolonic crohns disease the biopic study
$157,469
Mayo Clinic · Rochester, MN · 2024
Stenosis therapy and anti-fibrotic research (star) consortium
$151,705
Mayo Clinic · Rochester, MN · 2024
Development of a next-generation biomarker tool to accelerate the development of effective anti-fibrotic therapies
$115,500
Cedars-Sinai Medical Center · Los Angeles, CA · 2024
Very early onset inflammatory bowel disease (veoibd) precision molecular diagnoses to targeted therapies cedars-sinai
$75,165
Sage Bionetworks · Seattle, WA · 2024
Extension of veoibd data coordination to accelerate discovery of precision molecular diagnoses to targeted therapies
$55,571
University of Exeter · 2024
Advancing b-cell specific therapy by identifying b-cell reactive high affinity t cell receptors
$28,108
Medical University of South Carolina · Charleston, SC · 2024
Engineered dendritic cell based robust antigen specific therapy for type 1 diabetes
$2.1M
Ziv Medical Center Zefat · 2023
Pressure chamber for hyperbaric therapy, ziv medical center, safed.
$1.4M
Children'S Hospital Corporation · Boston, MA · 2023
Very early onset inflammatory bowel disease (veoibd): precision molecular diagnoses to targeted therapies: boston studies
$1.4M
The Cleveland Clinic Foundation · Cleveland, OH · 2023
Development of a next-generation biomarker tool to accelerate the development of effective anti-fibrotic therapies
$1.2M
University of Glasgow Court · 2023
Combination therapy with biologics and partial enteral nutrition in adults with active ileocolonic crohns disease: the biopic study
$1.1M
Trustees of Indiana University · Bloomington, IN · 2023
Molecular design and testing of glucose-responsive therapies
$988,042
Regents of the University of Minnesota · Minneapolis, MN · 2023
Standardized microbiota transplant therapy in crohns disease. Pilot trial.
$944,873
Cardiff University · 2023
T1d-plus: an adaptive trial platform for the study of combination therapies in new-onset t1d
$770,816
Katholieke Universiteit Te Leuven · 2023
Combination therapy of diet with biologicals for crohns disease: the oats study
$655,603
Care-for-Rare Foundation · 2023
Very early onset inflammatory bowel disease (veoibd): precision molecular diagnoses to targeted therapies: munich studies
$602,243
Seattle Children'S Hospital · Seattle, WA · 2023
Expanding use of engineered tregs in t1d therapy (phase 4)
$568,782
Johns Hopkins University · Baltimore, MD · 2023
Targeted, sustained release antifibrotic therapies for crohns disease patients
$548,276
The Hospital for Sick Children · 2023
Very early onset inflammatory bowel disease (veoibd): precision molecular diagnoses to targeted therapies-toronto studies
$494,231
The Scripps Research Institute · La Jolla, CA · 2023
Translation of microbiota mechanisms on nod2 for crohns disease therapies
$412,500
Medical University of South Carolina · Charleston, SC · 2023
Engineered dendritic cell based robust antigen specific therapy for type 1 diabetes
$397,123
Genome Research Limited for the Wellcome Sanger Institute · 2023
Scibd-response: massive-scale single-cell rna-sequencing to identify transcriptomic predictors of response to biologic therapies in crohns disease
$341,879
Board of Trustees of the Leland Stanford Junior University · Stanford, CA · 2023
Expansion & evaluation of echo for people with diabetes on intensive insulin therapy (iit)
$334,407
Mayo Clinic · Rochester, MN · 2023
Development of a next-generation biomarker tool to accelerate the development of effective anti-fibrotic therapies
$267,835
Alimentiv · 2023
Development of a next generation biomarker tool to accelerate the development of effective anti-fibrotic therapies
$251,522
Genome Research Limited for the Wellcome Sanger Institute · 2023
Scibd-response: massive-scale single-cell rna-sequencing to identify transcriptomic predictors of response to biologic therapies in crohns disease
$220,000
Icahn School of Medicine at Mount Sinai · New York City, NY · 2023
Very early onset inflammatory bowel disease (veoibd): precision molecular diagnoses to targeted therapies: mount sinai studies
$115,500
Cedars-Sinai Medical Center · Los Angeles, CA · 2023
Very early onset inflammatory bowel disease (veoibd): precision molecular diagnoses to targeted therapies: cedars-sinai
$73,424
Sage Bionetworks · Seattle, WA · 2023
Extension of veoibd data coordination to accelerate discovery of precision molecular diagnoses to targeted therapies
$1.7M
Board of Trustees of the Leland Stanford Junior University · Stanford, CA · 2022
Expansion & evaluation of echo for people with diabetes on intensive insulin therapy (iit)
$1.3M
Board of Trustees of the Leland Stanford Junior University · Stanford, CA · 2022
Expansion & evaluation of echo for people with diabetes on intensive insulin therapy (iit)
$1.2M
Seattle Children'S Hospital · Seattle, WA · 2022
Development of antigen-specific etreg therapy in t1d - stage 3 studies
$948,511
Alimentiv · 2022
Stenosis therapy and anti-fibrotic research (star) consortium
$696,962
Trustees of Indiana University · Bloomington, MI · 2022
Molecular design and testing of glucose-responsive therapies
$672,494
University of Glasgow Court · 2022
Combination therapy with biologics and partial enteral nutrition in adults with active ileocolonic crohns disease: the biopic study
$656,542
Katholieke Universiteit Leuven · 2022
Combination therapy of diet with biologicals for crohns disease: the oats study
$589,623
The Hospital for Sick Children · 2022
Very early onset inflammatory bowel disease (veoibd): precision molecular diagnoses to targeted therapies-toronto studies
$562,008
Johns Hopkins University · Baltimore, MD · 2022
Targeted, sustained release antifibrotic therapies for crohns disease patients
$330,000
Board of Trustees of the Leland Stanford Junior University · Stanford, CA · 2022
Expansion & evaluation of echo for people with diabetes on intensive insulin therapy (iit)
$190,161
University of Exeter · 2022
Advancing b-cell specific therapy by identifying b-cell reactive high affinity t cell receptors
$156,725
Genome Research Limited for the Wellcome Sanger Institute · 2022
Massive-scale single-cell rna-sequencing to identify transcriptomic predictors of response to biologic therapies in crohns disease
$155,544
The Cleveland Clinic Foundation · Cleveland, OH · 2022
Stenosis therapy and anti-fibrotic research (star) consortium
$155,376
The Regents of the University of Colorado Denver · Aurora, CO · 2022
Trial of early initiation of cgm-guided insulin therapy in t1d
$103,827
Mayo Clinic · Rochester, MN · 2022
Stenosis therapy and anti-fibrotic research (star) consortium
$54,000
Care-for-Rare Foundation · 2022
Very early onset inflammatory bowel disease (veoibd): precision molecular diagnoses to targeted therapies: munich studies
$1.2M
Children'S Hospital Corporation · Boston, MA · 2021
Veoibd precision molecular diagnoses to targeted therapies- boston
$793,072
Trustees of Indiana University · Bloomington, IN · 2021
Molecular design and testing of glucose-responsive therapies
$643,036
Care-for-Rare Foundation · 2021
Veoibd from precision molecular diagnoses to targeted therapies - munich
$452,624
The Sheba Fund for Health Services and Research (Ra) · 2021
Comprehensive individualized proactive therapy of crohns disease
$350,000
Rambam Health Corporation · 2021
Predicting and optimizing drug therapy in crohns disease
$220,000
Icahn School of Medicine at Mount Sinai · New York City, NY · 2021
Veoibd: precision diagnoses to targeted therapies: mount sinai studies
$174,998
The Milken Institute · Santa Monica, CA · 2021
Cures for life: patient access to cell and gene therapy
$173,250
Universitair Medisch Centrum Utrecht · 2021
Epithelial based diagnostics for targeted therapies of veoibd
$116,515
Alimentiv · 2021
Stenosis therapy and anti-fibrotic research (star) consortium
$115,500
Cedars-Sinai Medical Center · Los Angeles, CA · 2021
Veoibd precision molecular diagnoses to targeted therapies cedars-sinai

Top recipients

Repeat recipients are the strongest signal of whether a funder has an open door or quietly re-funds the same organizations.

Helmholtz Zentrum Munchen (Gmbh)42 grants · $52.3M
Blue Circle Health11 grants · $45.4M
Shaare Zedek Medical Center22 grants · $42.6M
Clalit Health Services37 grants · $41.7M
American Heart Association20 grants · $30.7M
Regents of the University of Minnesota16 grants · $30.4M
The End Fund4 grants · $30.0M
The Regents of the University of Colorado Denver49 grants · $22.5M
Mass General Brigham for the Brigham and Women'S Hospital7 grants · $21.5M
Catholic Relief Services-Usccb13 grants · $21.4M

Giving over time

$382.7M

2021

$427.5M

2022

$440.0M

2023

$439.5M

2024

Grant history

The 100 largest of 2,251 grants.

$22.5M
The End Fund · New York, NY · 2022
Neglected tropical disease: reaching the last mile
$15.6M
Blue Circle Health · Wilmington, DE · 2021
Creation of blue circle health for underserved communities with t1d
$12.6M
Regents of the University of Minnesota · Minneapolis, MN · 2021
Minnesota first responder aed project
$9.9M
Shaare Zedek Medical Center · 2021
The helmsley cancer center at shaare zedek medical center jerusalem
$9.0M
Mass General Brigham for the Brigham and Women'S Hospital · Boston, MA · 2023
Pen-plus expansion
$7.0M
Engineering Ministries International USA · Colorado Springs, CO · 2022
Alaska wash project
$7.0M
American Heart Association · Dallas, TX · 2024
American heart association center for telehealth
$6.8M
Mass General Brigham for the Brigham and Women'S Hospital · Boston, MA · 2024
Accelerating progress and promoting quality t1d care for the poorest billion through the global pen-plus partnership
$6.7M
Engineering Ministries International USA · Colorado Springs, CO · 2021
Alaska wash project
$6.6M
Nevada Department of Health and Human Services · Carson City, NV · 2022
Nevada first responder aed project
$6.6M
Geoscience Australia · 2022
Digital earth africa - sustainable uptake and impact
$6.4M
Commonwealth Healthcare Corporation · 2023
Cnmi chcc mri/medical equipment upgrade project
$6.1M
Yitzhak Shamir Medical Center · 2022
Expansion and renovation of the cancer institute at shamir medical center
$5.8M
Ben-Gurion University of the Negev · 2024
Construction of the leona m. And harry b. Helmsley charitable trust computer science building
$5.7M
Brigham and Women'S Hospital · Boston, MA · 2022
Pen-plus expansion
$5.6M
Nebraska Department of Health & Human Services · Lincoln, NE · 2021
Nebraska first responder aed project
$5.4M
Tzafon Medical Center · 2023
The helmsley rehabilitation center of the north
$5.3M
Iowa Department of Public Health · Des Moines, IA · 2021
Iowa first responder aed initiative
$5.3M
Hadassah Medical Organization · 2024
Equipping the new hadassah - helmsley medical center, netivot
$5.3M
Bridges To Prosperity · Denver, CO · 2021
Transformative connectivity in rural ethiopia
$5.2M
Shaare Zedek Medical Center · 2022
The helmsley cancer center at shaare zedek medical center jerusalem
$5.2M
Shaare Zedek Medical Center · 2023
Linear accelerators for the radiotherapy institute
$5.1M
The Baruch Padeh Medical Center Poriya · 2021
The helmsley rehabilitation center of the north
$5.0M
Regents of the University of Minnesota · Minneapolis, MN · 2022
Redefining the future of emergency medicine
$5.0M
Billings Clinic Foundation · Billings, MT · 2024
Billings clinic surgical intensive care unit
$5.0M
Kapiolani Health Foundation · Honolulu, HI · 2024
Martha b. Smith cancer & infusion center at kapiolani medical center for women & children
$5.0M
Stichting the Ocean Cleanup · 2024
Develop and scale technologies to rid the oceans of plastics
$5.0M
The Queens Medical Center · Honolulu, HI · 2024
The queen's medical center - west oahu cancer center expansion
$5.0M
Shaare Zedek Medical Center · 2023
Development of the helmsley surgical wing
$5.0M
Stichting the Ocean Cleanup · 2023
Develop and scale technologies to rid the oceans of plastics
$5.0M
Civica Foundation · Lehi, UT · 2021
Affordable insulin biosimilars
$4.9M
St Rose Dominican Health Foundation · Henderson, NV · 2023
Dignity health - st. Rose dominican - siena campus ecmo program
$4.9M
Fairview Health Services · Minneapolis, MN · 2023
Improving survival outcomes through university of minnesota medical center ecmo center of excellence
$4.9M
Regents of the University of Minnesota · Minneapolis, MN · 2023
Minnesota first responder aed project
$4.9M
Tel Aviv Sourasky Medical Center - Ichilov Hospital · 2024
Construction of the sheltered -5 floor of the north tower
$4.5M
Baptist Medical Centre · 2024
Elevating maternal and pediatric healthcare
$4.5M
Blue Circle Health · Wilmington, DE · 2024
Development of blue circle health
$4.5M
Blue Circle Health · Wilmington, DE · 2024
Development of blue circle health
$4.5M
The Baruch Padeh Medical Center Poriya · 2022
The helmsley rehabilitation center of the north
$4.4M
World Health Organization · 2022
Strengthening the capacity of the global diabetes compact
$4.4M
The Sheba Fund for Health Services and Research (Ra) · 2023
The helmsley center for innovative surgical training
$4.2M
Altru Health System · Grand Forks, ND · 2024
Altru health system ultrasound initiative
$4.2M
American Heart Association · Dallas, TX · 2023
American heart association center for telehealth
$4.2M
Jerusalem College of Technology · 2022
Helmsley faculty of life and health sciences building
$4.1M
The End Fund · New York, NY · 2023
Reaching the last mile fund expansion
$4.1M
Zefat Academic College · 2021
Equipping zefat academic college's inst. For adv. Health training & ed.
$4.1M
Clalit Health Services · 2022
A new neonatal center for israels southern periphery at soroka medical center
$4.0M
Holy Rosary Healthcare Foundation · Miles City, MT · 2022
Holy rosary healthcare comprehensive cancer center
$4.0M
Blue Circle Health · Wilmington, DE · 2024
Development of blue circle health
$3.9M
Wilcox Health Foundation · Lihue, HI · 2024
Wilcox medical center equipment revitalization project
$3.9M
Clalit Health Services · 2021
Medical equipment for carmel medical center in haifa, israel
$3.9M
Hadassah Medical Organization · 2022
Creating and equipping a new comprehensive diagnostic and interventional imaging center
$3.8M
Clalit Health Services · 2022
Yoseftal hospital addition
$3.8M
St Alexius Medical Center · Bismarck, ND · 2024
Chi st. Alexius health ultrasound initiative
$3.7M
New York University School of Medicine · New York, NY · 2023
Tamale education and innovation center for health
$3.7M
Central Montana Medical Facilities · Lewistown, MT · 2023
Cancer center at central montana medical center
$3.7M
T1d Exchange · Boston, MA · 2021
Data approach to improve quality and outcomes for individuals with t1d
$3.7M
Bhsh System · Grand Rapids, MI · 2022
Study the feasibility of telerobotic heart attack and stroke interventions
$3.7M
Helmholtz Zentrum Munchen (Gmbh) · 2021
Identification of infants with high risk of t1d - primary prevention
$3.6M
The Sheba Fund for Health Services and Research (Ra) · 2022
The helmsley center for innovative surgical training
$3.5M
Hillel Yaffe Medical Center · 2024
Construction of pet-ct institute
$3.5M
Maccabi Healthcare Services · 2021
Da vinci 4xi system dual console surgical robot and sterilization equip.
$3.5M
State of Nevada Department of Division of State Parks · Carson City, NV · 2024
Valley of fire visitor center
$3.5M
State of Nevada Department of Division of State Parks · Carson City, NV · 2023
Ice age fossil state park trails and outdoor amenities
$3.5M
State of Nevada Department of Division of State Parks · Carson City, NV · 2023
Valley of fire visitor center
$3.5M
Blue Circle Health · Wilmington, DE · 2022
Development of blue circle health
$3.5M
The Broad Institute · Cambridge, MA · 2024
Novel therapeutic approaches for crohns disease
$3.5M
Blue Circle Health · Wilmington, DE · 2023
Development of blue circle health
$3.5M
Indiana University · Indianapolis, IN · 2021
Ampath model replication in ghana
$3.5M
Central Montana Medical Facilities · Lewistown, MT · 2022
Cancer center at central montana medical center
$3.3M
Bar Ilan University in Israel · 2024
The leona m. And harry b. Helmsley energy prototype lab at bar-ilan university
$3.3M
New Venture Fund · Washington, DC · 2021
Type 1 diabetes camps project (2022 - 2024)
$3.3M
St Luke Health Care Foundation · West Chicago, IL · 2024
Hope center for women and children
$3.2M
Bar Ilan University · 2023
The leona m. And harry b. Helmsley energy prototype lab at bar-ilan university
$3.2M
Fairview Health Services · Minneapolis, MN · 2024
Improving survival outcomes through university of minnesota medical center ecmo center of excellence
$3.2M
Hillel Yaffe Medical Center · 2024
Eye institute and ambulatory surgery center
$3.1M
National Park Foundation · Washington, DC · 2022
Little bighorn battlefield national monument visitor center
$3.1M
World Health Organization · 2024
Strengthening the capacity of the global diabetes compact
$3.1M
World Health Organization · 2024
Strengthening integrated prevention and control of chronic and severe ncds in the who african region, using t1d, scd, arf, and rhd as entry points
$3.1M
Renown Health Foundation · Reno, NV · 2022
Simulation and innovation center at renown health
$3.1M
Clinton Health Access Initiative · Boston, MA · 2023
Improving medical oxygen production and utilization
$3.0M
Brigham and Women'S Hospital · Boston, MA · 2021
Global partnership to achieve universal access for t1d and ncds
$3.0M
St Luke Health Care Foundation · West Chicago, IL · 2023
Hope center for women and children
$3.0M
Trinity Health · Minot, ND · 2024
Trinity health ultrasound initiative
$3.0M
The Weizmann Institute of Science · 2024
Early childhood development and community center at the weizmann institute of science
$3.0M
Tel-Aviv University · 2023
Helmsley medical simulation center
$3.0M
The Weizmann Institute of Science · 2023
Early childhood development and community center at the weizmann institute of science
$3.0M
Diabetes Nsw · 2022
Improvements in outcomes for young people with diabetes in less-resourced countries
$3.0M
The Jewish Agency for Israel · 2022
Flights for new immigrants from russia
$3.0M
Avera McKennan Hospital and University Health Center · Sioux Falls, SD · 2021
Avera behavioral health center expansion
$3.0M
Jdrf T1d Fund Llc · Boston, MA · 2021
Jdrf t1d fund phase iii
$3.0M
South Dakota Parks & Wildlife Foundation · Pierre, SD · 2021
Custer state park bison center
$3.0M
The Broad Institute · Cambridge, MA · 2021
Novel therapeutic approaches for crohns disease
$3.0M
Children'S Mercy Hospital · Kansas City, MO · 2022
Type 1 diabetes rapid learning lab
$3.0M
Kmr Advancement of Medical Centers Ltd · 2021
Establishment of the health discovery tower
$2.9M
Helmholtz Zentrum Munchen (Gmbh) · 2023
Continuation of the gppad-02-study: identification of infants with increased type 1 diabetes risk for enrollment into primary prevention trials
$2.9M
Mass General Brigham for the Brigham and Women'S Hospital · Boston, MA · 2024
Real-time post-op touchless, remote monitoring in crohns disease the sapphire trial
$2.9M
Sanford · Fargo, ND · 2022
Sanford health ultrasound project
$2.9M
World Health Organization · 2023
Strengthening integrated prevention and control of chronic and severe ncds in the who african region, using t1d, scd, arf, and rhd as entry points
$2.9M
Jerusalem College of Technology · 2021
Helmsley faculty of life and health sciences building

View all 2,251 grants →

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Search funders like this one

Source: IRS Form 990-PF, Part XV, as filed by the foundation. These are grants already paid — a record of what this funder backs, not an open call.