Funding search · EIN 522396428 · Grantmaking charity · Wellesley Hills, MA

Alzheimer'S Disease Research Foundation

$100.1M
in grants paid: 448
grants: 99
recipients: 2022–2025
filing years

Funding pattern

What this funder pays for, at what size, and how to position adjacent work. Read from their filings, with every number checked against the record.

Recent grants

The 100 largest recent grants from this foundation’s filings, newest year first.

$2.0M
Massachusetts General Hospital · Boston, MA · 2025
The curealz alzheimer's genome project
$575,000
Brigham and Women'S Hospital · Boston, MA · 2025
Apoe4 accelerates cd8 exhaustion via glucocorticoid signaling in alzheimer's female carriers
$431,250
Brigham and Women'S Hospital · Boston, MA · 2025
A new model of microglia genetic perturbation in vivo to screen all risk factors associated with alzheimer's disease
$402,500
University of Michigan · Ann Arbor, MI · 2025
Non-invasive modulation of microglia gene expression using peripherally administered antibody conjugates
$402,500
Weill Medical College of Cornell University · New York, NY · 2025
Sex-biased tlr7 signaling in demyelination and its inhibition by small molecules
$402,492
University of California Irvine · Irvine, CA · 2025
Proteomic signatures of cerebrovascular neuropathology in down syndrome with alzheimer disease
$398,521
University of Michigan · Ann Arbor, MI · 2025
Utilizing heterogeneous mouse models to discover mechanisms underlying caloric restriction (cr) on cognitive outcomes
$345,000
Washington University in St Louis · St Louis, MO · 2025
Bee: meningeal mast cell control of csf dynamics in homeostasis and alzheimer's disease
$345,000
Washington University in St Louis · St Louis, MO · 2025
Bac: identifying age-related proteomic changes that predict future onset of amyloid-beta aggregation in alzheimer's disease
$345,000
Washington University in St Louis · St Louis, MO · 2025
Apoe consortium: investigating potential cell autonomous neuroprotection of apoe protective variants
$344,528
Boston Children'S Hospital · Boston, MA · 2025
Nic: effects of peripheral inflammation on myeloid cell function in alzheimer's disease
$327,501
The McLean Hospital Corporation · Belmont, MA · 2025
Expanding postmortem brain resources for alzheimer's disease in diverse populations
$320,033
Duke University School of Medicine · Durham, NC · 2025
Utility of blood based markers for predicting aria and its course in mci and ad subjects undergoing routine clinical treatment with amyloid-directed antibodies
$300,000
Massachusetts General Hospital · Boston, MA · 2025
Understanding human brain resilience to alzheimer's pathology
$287,673
National Institute of Neurological Disorders & Stroke · Bethesda, MD · 2025
Bee: high-resolution mri of the brain borders
$287,500
Massachusetts General Hospital · Boston, MA · 2025
Bee: human 3d neuro-vascular interaction and meningeal lymphatics models with application to alzheimer's disease
$287,500
University of Rochester · Rochester, NY · 2025
Bee: does slym failure compromise glymphatic clearance in alzheimer's disease?
$287,500
Washington University in St Louis · St Louis, MO · 2025
Bac: brain region and cell-type specific aging from accelerated to resilient trajectories
$287,500
Regents of the University of California San Diego · La Jolla, CA · 2025
Bee: how does vascular fatty acid metabolism regulate the pathophysiology of alzheimer's disease?
$287,500
Regents of the University of California San Diego · La Jolla, CA · 2025
Nic: mechanisms mediating microglia sensing of peripheral inflammation
$287,500
New York University School of Medicine · New York, NY · 2025
Nic: astrocyte inflammatory contributions to ad
$287,500
Stanford University · Redwood City, CA · 2025
Bac: choroid plexus aging and alzheimer's disease
$287,499
Washington University in St Louis · St Louis, MO · 2025
Bac: establishing isogenic models of human neuron aging and pathways relevant for alzheimer's disease
$287,490
University of California Irvine · Irvine, CA · 2025
Nic: examining the impact of peripherally derived human macrophages in ad pathogenesis
$287,477
Massachusetts Institute of Technology · Cambridge, MA · 2025
Bac: investigating lipidomic perturbations in the csf with age and alzheimer's disease progression: toward mechanistic insights and accessible lipid biomarkers
$286,466
University of California Davis · Davis, CA · 2025
Nic: impact of ad polygenic risk score on microglial response to peripheral inflammation
$284,678
University of Pennsylvania · Philadelphia, PA · 2025
Apoe consortium: cell autonomous roles of protective apoe variants in microglia responding to amyloid pathology
$271,375
University of Alabama at Birmingham · Birmingham, AL · 2025
Expanding deep south inclusion in the uab adrc neuropathology core brain bank
$264,500
Boston Children'S Hospital · Boston, MA · 2025
Bee: neuroinflammation at the choroid plexus in alzheimer's disease (supplement)
$258,750
Weill Medical College of Cornell University · New York, NY · 2025
A three-dimensional tissue model linking tau tangles, ab and microglial cd33- isoform state to gene- and isoform-expression dysregulation (cfsf supplement)
$258,750
University of Virginia · Charlottesville, VA · 2025
The role of planar cell polarity proteins in tau oligomer-induced synapse degeneration (cfsf supplement)
$258,750
Massachusetts General Hospital · Boston, MA · 2025
Alzheimer's disease tau consortium: toxic consequences of early tau seeding (cfsf supplement)
$258,750
Massachusetts General Hospital · Boston, MA · 2025
Exploring novel drug candidates for alzheimer's disease through integrative pathway analysis and validation in 3d cellular models (cfsf supplement)
$258,615
Gladstone Institutes · San Francisco, CA · 2025
Decoding protein transport across the blood-brain barrier to enable new alzheimer's therapies (cfsf supplement)
$258,573
Gladstone Institutes · San Francisco, CA · 2025
Developing cell-type-specific enhancer-aav vectors to characterize and restore ab- and tau-dependent circuit and cognitive deficits in humanized alzheimer's mouse models (cfsf supplement)
$252,076
Massachusetts General Hospital · Boston, MA · 2025
Menopause and related midlife risk factors and their impact on pathology and cognition - the whimsyad study
$230,000
The Broad Institute · Cambridge, MA · 2025
Investigating alzheimer's disease-associated membrane biology in microglia and neurons
$230,000
Regents of the University of California San Diego · La Jolla, CA · 2025
App gene dose-mediated dysregulation of the endolysosomal network acts compromise synaptic structure and function leading to alzheimer disease in down syndrome
$230,000
Mayo Clinic Jacksonville · Jacksonville, FL · 2025
Unraveling mixed pathology and its impact on the proteome in alzheimer's disease
$230,000
Icahn School of Medicine at Mount Sinai · New York, NY · 2025
Investigating the pathogenetic role of microglial mef2c in alzheimer's disease across the lifespan: developmental priming vs. Adult response to injury
$230,000
President and Fellows of Harvard College · Cambridge, MA · 2025
Moving the cure alzheimer genome project beyond simple associations: integrating functional information, fine-mapping and causal inference approaches into the family-based analysis of the cure alzheimer whole-genome seq… read allMoving the cure alzheimer genome project beyond simple associations: integrating functional information, fine-mapping and causal inference approaches into the family-based analysis of the cure alzheimer whole-genome sequencing (wgs) family study less
$230,000
Massachusetts General Hospital · Boston, MA · 2025
Adam10 cleavage of app: physiological function in brain and therapeutic potential for alzheimer's disease
$230,000
University of California Irvine · Irvine, CA · 2025
Engineered car-macrophages to clear tau
$230,000
University of Texas Southwestern Medical Center · Dallas, TX · 2025
Engineered car-macrophages to clear tau
$228,900
Brigham and Women'S Hospital · Boston, MA · 2025
Do classical complement activation and the route of administration of anti-amyloid antibodies contribute to vascular side effects known as aria?
$210,962
New York University School of Medicine · New York, NY · 2025
Mechanisms of astrocyte-derived lipid toxicity in alzheimer's disease
$204,656
Duke University School of Medicine · Durham, NC · 2025
Contributions of il34 signaling to microglial function and alzheimer's pathology in mice
$201,251
University of Michigan · Ann Arbor, MI · 2025
Morphological, electrophysiological, and transcriptional characterization of single neurons from resilient and susceptible models of human ad
$201,250
Beth Israel Deaconess Medical Center · Boston, MA · 2025
Integrating single-cell genomics for pathways to protection and resilience against alzheimer's disease
$201,250
Emory University · Atlanta, GA · 2025
Mitochondrial alzheimer's risk factors control apoe expression and secretion
$201,250
Gladstone Institutes · San Francisco, CA · 2025
Decoding protein transport across the blood-brain barrier to enable new alzheimer's therapies
$201,250
Augusta University Research Institute · Augusta, GA · 2025
The impact of soluble dietary fiber on tau-mediated neurodegeneration in a mouse model of tauopathy
$201,250
Gladstone Institutes · San Francisco, CA · 2025
Developing cell-type-specific enhancer-aav vectors to characterize and restore ab- and tau-dependent circuit and cognitive deficits in humanized alzheimer's mouse model
$201,250
Icahn School of Medicine at Mount Sinai · New York, NY · 2025
Investigating the association between clonal hematopoiesis and alzheimer's disease
$201,250
Icahn School of Medicine at Mount Sinai · New York, NY · 2025
Role of psychosocial stress in alzheimer's disease
$201,250
Johns Hopkins University · Baltimore, MD · 2025
A temporally aligned multimodal framework for individualized alzheimer's disease risk assessment and deep learning-driven prognosis
$201,250
Johns Hopkins University · Baltimore, MD · 2025
From molecular heterogeneity to predictive medicine: transforming neurodegenerative disease research through spatial multi-omics and interpretable ai
$201,250
Columbia University · New York, NY · 2025
Semaphorin regulation of disease-associated microglia in alzheimer's disease
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Rin3 and bin1 interaction connects endosomal pathology with amyloid pathology
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Tau and b-amyloid are innate immune antimicrobial peptides in the brain
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Precision gene therapy targeting microglia in alzheimer's disease
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Engineering a human region-specific system to probe apoe-linked cellular vulnerability and resilience in alzheimer's disease
$201,250
Carnegie Mellon University · Pittsburgh, PA · 2025
Interpreting alzheimer's disease-associated genetic variation at enhancer regions
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Exploring novel drug candidates for alzheimer's disease through integrative pathway analysis and validation in 3d cellular models
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Centenarian microglia reveal a neprilysin-dependent mechanism of resilience in alzheimer's disease
$201,250
Brigham and Women'S Hospital · Boston, MA · 2025
Viral infections and alzheimer's disease risk in women
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Identifying sex-aware x-chromosome targets for preclinical alzheimer's disease
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Circuit dynamics in apoe4 mice
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Interneuron therapy for alzheimer's disease
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Development of a flap-targeted neuroimmune pet tracer for imaging microglia in ad
$201,250
Mayo Clinic Jacksonville · Jacksonville, FL · 2025
Linking sleep dysfunction to tau-related degeneration across ad variants
$201,250
Mayo Clinic Jacksonville · Jacksonville, FL · 2025
The multi-omic roadmap to neuronal senescence in alzheimer's disease
$201,250
Columbia University · New York, NY · 2025
Noncoding translation feedback loop in alzheimer's disease
$201,250
Icahn School of Medicine at Mount Sinai · New York, NY · 2025
Investigating mef2c transcription factor as therapeutic target to reprogram pathological microglial states in alzheimer's disease
$201,250
Mayo Clinic Jacksonville · Jacksonville, FL · 2025
Evaluating the contribution of tdp-43 dysfunction and cryptic mis-splicing to ad pathogenesis
$201,250
Mayo Clinic Jacksonville · Jacksonville, FL · 2025
Elucidating the protective effects of apoe2 in the presence of apoe 4 gene allele in animal models
$201,250
Mayo Clinic Rochester · Rochester, MN · 2025
Bridging the gap: sex-specific drivers of senescence underlying neurodegeneration
$201,250
Memorial Sloan Kettering Cancer Center · New York, NY · 2025
Development and mechanism of autophagy activators for treatment of alzheimer's disease
$201,250
New York University School of Medicine · New York, NY · 2025
Midlife autoantibody profiles and the risk of late-onset alzheimer's disease in women
$201,250
New York University School of Medicine · New York, NY · 2025
Viral infections and alzheimer's disease risk in women
$201,250
Northwestern University · Chicago, IL · 2025
Sex-specific mechanisms of neuroinflammation in the alzheimer's disease hypothalamus
$201,250
Northwestern University · Chicago, IL · 2025
Role of tau in presynaptic dysfunction during the cellular phase of alzheimer's disease
$201,250
President and Fellows of Harvard College · Cambridge, MA · 2025
Meningeal tregs in individuals with vs without alzheimer's disease
$201,250
Regents of the University of California San Diego · La Jolla, CA · 2025
Dysregulation of signaling on post synaptic density scaffolds in alzheimer's disease
$201,250
Regents of the University of California San Diego · La Jolla, CA · 2025
Son-dependent nuclear speckle rejuvenation: a novel proteostasis-based therapeutic strategy for alzheimer's disease
$201,250
The Regents of the University of California San Francisco · San Francisco, CA · 2025
Neuronal mechanisms driving synapse loss in alzheimer's disease
$201,250
The Regents of the University of California San Francisco · San Francisco, CA · 2025
Probing the molecular underpinnings of how g protein-coupled receptor adgrg1 mediates protective responses to alzheimer's disease
$201,250
The Regents of the University of California San Francisco · San Francisco, CA · 2025
Role of platelet-derived factors in ameliorating alzheimer's disease pathology
$201,250
The Salk Institute for Biological Studies · La Jolla, CA · 2025
The role of astrocyte-secreted igfbp2 in the progression of alzheimer's disease
$201,250
University of California Davis · Davis, CA · 2025
Deciphering phosphorylation-dependent tau envelope dysfunction to prevent alzheimer's neurodegeneration
$201,250
University of South Florida · Tampa, FL · 2025
Bin1 in microglial heterogeneity along ad progression and microglial function
$201,250
University of Texas Health Science Center at San Antonio · San Antonio, TX · 2025
How do microglia contribute to the spread of tau pathology in alzheimer's disease?
$201,250
University of Texas Health Science Center at San Antonio · San Antonio, TX · 2025
Digital neuropathology infrastructure for precision medicine in south texas hispanic ad/adrd populations
$201,250
University of Texas Health Science Center at San Antonio · San Antonio, TX · 2025
Cognitively healthy nonagenarians in the cross cohort collaboration (ccc)
$201,250
University of Virginia · Charlottesville, VA · 2025
Microglial mitochondrial dysfunction and tau toxicity in alzheimer's disease
$201,250
University of Virginia · Charlottesville, VA · 2025
Impact of dna damage-mediated sting activation on myelin function in an alzheimer's disease animal model
$201,250
University of Virginia · Charlottesville, VA · 2025
Elucidating the role of emerging genomic stress sensors in ad
$201,250
Washington University in St Louis · St Louis, MO · 2025
Sleep reinforces homeostatic set-points in neural activity and mitigates neurodegenerative disease
$201,250
Washington University in St Louis · St Louis, MO · 2025
Development of small molecule inhibitors of cholesterol 25-hydroxylase
$201,250
Washington University in St Louis · St Louis, MO · 2025
Targeting reactive astrocytes ampk signaling to suppress inflammation in alzheimer's disease

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Source: IRS Form 990, Schedule I, as filed by this organization. These are grants already paid. Unlike private foundations, grantmaking charities and associations often run formal grant programs with real application cycles — check their website for current opportunities. Grants paid directly to individuals are reported to the IRS only as totals, so they do not appear as named lines here.