Funding search · substance use and addiction · California
Who funds substance use and addiction work in California
15 funders have a record of paying for substance use and addiction work by California recipients: 89 grants totaling $7.4M, most recently in 2025 — mostly grantmaking charities, which often run real application cycles. The largest by matched giving are California Institute for Behavioral ($474,463), Foundation for Opioid Response Efforts ($1.4M) and Mind Oc ($511,858).
From IRS Form 990-PF and 990 Schedule I filings, 2019–2025. Grants already paid to California recipients — evidence of what these funders back, not open calls.
California Institute for BehavioralSacramento, CACharity · may take applications
19 matching grants · $474,463 · through 2024Largest: $61,368 to DREAM YOUTH CLINIC — california youth opioid response grant (yor california)
Largest: $215,050 to RAND CORPORATION — buprenorphine treatment for opioid use disorder (oud) during the covid-19 pandemic and the role of state policy changes
Mind OcIrvine, CACharity · may take applications
8 matching grants · $511,858 · through 2024Largest: $97,443 to KOREAN COMMUNITY SERVICE — youth opioid use disorder
Mental Health AmericaAlexandria, VACharity · may take applications
5 matching grants · $693,830 · through 2024Largest: $197,330 to THE REGENTS OF THE UNIVERSITY OF CALIFORNIA AT IRVINE — substance use disorder research grant
Kaiser Foundation HospitalsOakland, CACharity · may take applications
7 matching grants · $270,000 · through 2024Largest: $150,000 to Reach Out West End — riverside county opioid awareness & prevention pro
Vital StrategiesNew York, NYCharity · may take applications
5 matching grants · $1.2M · through 2024Largest: $380,000 to DREAM CORPSDREAMORG — overdose prevention (opioid)
Largest: $200,000 to California Health Collaborative — maternal wellness (perinatal substance use task force) program
Largest: $250,000 to LOMA LINDA UNIVERSITY — emergency management strategies to decrease opioid deaths
Largest: $75,000 to NEW DIRECTIONS FOR WOMEN FOUNDATION — fund need based scholarships in support of addiction treatment services for women
Largest: $225,000 to CURE ADDICTION NOW — dedicated to the understanding, treatment and ultimate cure of "drug addiction", scientifically known as substance use disorder (sud) while simultaneously addressing the importance…
Rja FoundationPlaya Del Rey, CA
4 matching grants · $110,000 · through 2024Largest: $50,000 to CLARE MATRIX — provide help to people affected by alcohol, substance use and behavioral health issues
Paramedic ResourcesSacramento, CACharity · may take applications
4 matching grants · $156,862 · through 2023Largest: $65,000 to CONEJO HEALTH — opioid prevention
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Start with one paperBroader: substance use and addiction funders nationally · all California-based grantmakers