Funding search · substance use and addiction · North Carolina
Who funds substance use and addiction work in North Carolina
15 funders have a record of paying for substance use and addiction work by North Carolina recipients: 112 grants totaling $18.9M, most recently in 2024 — mostly private foundations, plus grantmaking charities. The largest by matched giving are Dogwood Health Trust ($7.7M), The Duke Endowment ($4.7M) and Vital Strategies ($2.7M).
From IRS Form 990-PF and 990 Schedule I filings, 2019–2025. Grants already paid to North Carolina recipients — evidence of what these funders back, not open calls.
Largest: $20,272 to GRAHAM COUNTY — this grant will support graham county to collaborate with the eastern band of cherokee indians and an expert consultant experienced in community-based harm reduction and substance …
Largest: $400,000 to ORTHOCAROLINA RESEARCH INSTITUTE — to reduce opioid prescriptions by testing and evaluating opioid-free surgical procedures and to disseminate findings nationally.
Vital StrategiesNew York, NYCharity · may take applications
14 matching grants · $2.7M · through 2024Largest: $127,128 to UNC INJURY PREVENTION RESEARCH CENTER (IPRC) OPIOID DATA LAB — overdose prevention (opioid)
The Institute for IntergovernmentalTallahassee, FLCharity · may take applications
8 matching grants · $571,309 · through 2024Largest: $141,226 to COASTLANDS MINISTRIES — preventing and reducing overdose deaths associated with opioids
Largest: $220,000 to UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL — justice core: implementing evidence-based substance use disorder treatment through alternatives to perinatal incarceration
Governor'S Institute On Substance AbuseRaleigh, NCCharity · may take applications
4 matching grants · $166,875 · through 2024Largest: $55,600 to UNC- SON — the purpose of this assistance is to support the unc-son to continue to implement the "cdc quality improvement and coordinated care project" (referred to as cdc qi project) in part…
Largest: $5,000 to WILL'S PLACE — medical, resource center for individuals recovering from substance use disorder
Largest: $10,000 to CAPSTONE RECOVERY CENTER INC — recovery from substance use disorder and deteriorated mental health
The McKnight Endowment Fund for NeuroscienceMinneapolis, MN
2 matching grants · $200,000 · through 2023Largest: $100,000 to University of North Carolina - Chapel Hill — elucidating the neural basis of pain unpleasantness: circuits and new therapeutics to end the dual epidemic of chronic pain and opioid addiction. principal investigator: gregory sc…
Largest: $66,633 to RESEARCH TRIANGLE INSTITUTE — to conduct the first comprehensive study of how law enforcement agencies are responding to the opioid overdose crisis.
Carolinas Care PartnershipCharlotte, NCCharity · may take applications
3 matching grants · $155,708 · through 2024Largest: $83,733 to McLeod Addictive Disease Center — for in-patient substance abuse treatment
McLeod Centers for WellbeingCharlotte, NCCharity · may take applications
3 matching grants · $862,921 · through 2024Largest: $398,986 to INTEGRATED CARE OF GREATER HICKORY — provide substance use disorder treatment, housing, and transportation
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Start with one paperBroader: substance use and addiction funders nationally · all North Carolina-based grantmakers

