Funding search · substance use and addiction · South Carolina
Who funds substance use and addiction work in South Carolina
10 funders have a record of paying for substance use and addiction work by South Carolina recipients: 22 grants totaling $2.8M, most recently in 2024 — mostly private foundations, plus grantmaking charities. The largest by matched giving are The Duke Endowment ($1.9M), The Institute for Intergovernmental ($808,775) and John I Smith Charities ($45,000).
From IRS Form 990-PF and 990 Schedule I filings, 2019–2025. Grants already paid to South Carolina recipients — evidence of what these funders back, not open calls.
Largest: $355,000 to PRISMA HEALTH-UPSTATE — to pilot an intensive case management program for pregnant and postpartum women struggling with substance use disorder.
The Institute for IntergovernmentalTallahassee, FLCharity · may take applications
3 matching grants · $808,775 · through 2022Largest: $328,549 to PRISMA HEALTH - UPSTATE — preventing and reducing overdose deaths associated with opioids
Largest: $25,000 to FAVOR UPSTATE — provide community outreach and substance use disorder education and services to upstate sc
Largest: $2,500 to CHASE HUECHTKER FOUNDATION CHASING THE WAKE — to raise awareness about the opioid epidemic and reducing the stigma associated with mental health and substnace use disorders.
KershawhealthCamden, SCCharity · may take applications
1 matching grant · $63,416 · through 2022Largest: $63,416 to THE ALPHA CENTER — sc opioid recovery g
Eastern Carolina Community FoundationFlorence, SCCharity · may take applications
1 matching grant · $9,100 · through 2024Largest: $9,100 to POTTER HOUSE RECOVERY — provide highest quality substance use disorder treatment services and deliver them with passion, and integrity.
Spartanburg Regional Healthcare SystemSpartanburg, SCCharity · may take applications
1 matching grant · $19,500 · through 2021Largest: $19,500 to SRHS - UNION MEDICAL CENTER NURSING — to promote awareness and education on the opioid crisis through various media outlets and marketing materials in partnership with the union county behavioral health taskforce
Largest: $5,000 to PALMETTO FOUNDATION FOR PREVENTION & RECOVERY — to help continue the work to combat substance use in and around the community
Largest: $5,000 to THE FAMILY EFFECT — funding for a community room at a residential addiction treatment center for pregnant women, young mothers & their children
Largest: $2,500 to IRONWOLF RECOVERY — to support family programming to help individuals achieve long-term recovery from substance use disorders
This is one topic and one state. PaperOrbit reads your actual paper and searches on everything in it — then explains why each funder fits.
Start with one paperBroader: substance use and addiction funders nationally · all South Carolina-based grantmakers

