Funding search · EIN 522396428 · Wellesley Hills, MA

Alzheimer'S Disease Research Foundation

Name: Alzheimer'S Disease Research Foundation grants, 2022–2025
Creator: PaperOrbit
License: https://www.irs.gov/charities-non-profits/exempt-organization-public-disclosure-and-availability-requirements

A grantmaking public charity (files IRS Form 990, Schedule I). Charities like this often run real grant programs with application cycles.

448
grants reported: $100.1M
total given: 2022–2025
filing years: $201,250
median grant

Based on grants this organization reported to the IRS for tax years 2022–2025. This is what they filed, not a complete record of their giving, and recent years may be incomplete because filings lag.

What they fund

disease alzheimer role brain cell alzheimers apoe human

Funder website ↗Full IRS filings ↗How this is built Report an error

Funding pattern

What this funder pays for, at what size, and how to position adjacent work. Read from their filings, with every number checked against the record.

Top recipients

Repeat recipients are the strongest signal of whether a funder has an open door or quietly re-funds the same organizations.

Massachusetts General Hospital72 grants · $21.9M
Washington University in St Louis35 grants · $7.4M
Brigham and Women'S Hospital18 grants · $5.1M
Washington University17 grants · $3.8M
University of Virginia13 grants · $2.5M
Mayo Clinic Jacksonville12 grants · $2.4M
Icahn School of Medicine at Mount Sinai13 grants · $2.3M
Weill Medical College of Cornell University9 grants · $2.1M
University of California Irvine8 grants · $2.1M
Northwestern University9 grants · $2.0M

Giving over time

$18.9M

2022

$23.1M

2023

$24.2M

2024

$33.8M

2025

Grant history

The 100 largest of 448 grants.

$2.0M
Massachusetts General Hospital · Boston, MA · 2025
The curealz alzheimer's genome project
$2.0M
Massachusetts General Hospital · Boston, MA · 2024
The curealz alzheimer's genome project
$2.0M
Massachusetts General Hospital · Boston, MA · 2023
The curealz alzheimer's genome project
$2.0M
Massachusetts General Hospital · Charlestown, MA · 2022
Thecurealzalzheimers genome project
$575,000
Brigham and Women'S Hospital · Boston, MA · 2025
Apoe4 accelerates cd8 exhaustion via glucocorticoid signaling in alzheimer's female carriers
$575,000
Brigham and Women'S Hospital · Boston, MA · 2024
Apoe: apoe4 accelerates cd8 exhaustion via glucocorticoid signaling in alzheimer's female carriers
$431,250
Brigham and Women'S Hospital · Boston, MA · 2025
A new model of microglia genetic perturbation in vivo to screen all risk factors associated with alzheimer's disease
$431,250
Brigham and Women'S Hospital · Boston, MA · 2023
A new model of microglia genetic perturbation in vivo to screen all risk factors associated with alzheimer's disease
$402,500
University of Michigan · Ann Arbor, MI · 2025
Non-invasive modulation of microglia gene expression using peripherally administered antibody conjugates
$402,500
Weill Medical College of Cornell University · New York, NY · 2025
Sex-biased tlr7 signaling in demyelination and its inhibition by small molecules
$402,500
Weill Medical College of Cornell University · New York, NY · 2024
Sex-biased tlr7 signaling in demyelination and its inhibition by small molecules
$402,492
University of California Irvine · Irvine, CA · 2025
Proteomic signatures of cerebrovascular neuropathology in down syndrome with alzheimer disease
$398,521
University of Michigan · Ann Arbor, MI · 2025
Utilizing heterogeneous mouse models to discover mechanisms underlying caloric restriction (cr) on cognitive outcomes
$345,000
Washington University in St Louis · St Louis, MO · 2025
Apoe consortium: investigating potential cell autonomous neuroprotection of apoe protective variants
$345,000
Washington University in St Louis · St Louis, MO · 2025
Bee: meningeal mast cell control of csf dynamics in homeostasis and alzheimer's disease
$345,000
Washington University in St Louis · St Louis, MO · 2025
Bac: identifying age-related proteomic changes that predict future onset of amyloid-beta aggregation in alzheimer's disease
$345,000
Northwestern University · Chicago, IL · 2024
Mbc: interaction of the microbiome with astrocytes and amyloid pathology
$345,000
Washington University in St Louis · St Louis, MO · 2024
Apoe: investigating potential cell autonomous neuroprotection of apoe protective variants
$345,000
Washington University in St Louis · St Louis, MO · 2024
Bee: meningeal mast cell control of csf dynamics in homeostasis and alzheimer's disease
$345,000
Massachusetts General Hospital · Boston, MA · 2023
Neuroprotective effects of the exercise hormone irisin in alzheimer's disease
$345,000
Northwestern University · Chicago, IL · 2023
Mbc: interaction of the microbiome with astrocytes and amyloid pathology
$345,000
Washington University · St Louis, MO · 2023
Apoe consortium: role of apoe isoforms in immune responses in a model of tauopathy
$345,000
Washington University · St Louis, MO · 2023
Bee: crosstalk of cns barriers and clearance routes in homeostasis and alzheimer's disease
$345,000
Washington University · St Louis, MO · 2022
Bee: crosstalk of cns barriers and clearance routes in homeostasis and alzheimers disease
$345,000
Washington University · St Louis, MO · 2022
Apoe consortium: role of apoe isoforms in immune responses in a model of tauopathy
$344,528
Boston Children'S Hospital · Boston, MA · 2025
Nic: effects of peripheral inflammation on myeloid cell function in alzheimer's disease
$344,085
Boston Children'S Hospital · Boston, MA · 2023
Nic: effects of peripheral inflammation on myeloid cell function in alzheimer's disease
$327,501
The McLean Hospital Corporation · Belmont, MA · 2025
Expanding postmortem brain resources for alzheimer's disease in diverse populations
$320,033
Duke University School of Medicine · Durham, NC · 2025
Utility of blood based markers for predicting aria and its course in mci and ad subjects undergoing routine clinical treatment with amyloid-directed antibodies
$307,500
Whitehead · Cambridge, MA · 2022
Circuits: impact of epigenetic and cellular variants on alzheimers disease pathology
$301,069
University of Southern California · Los Angeles, CA · 2023
Air pollution and ad risk interact with premature aging of neural stem cells and apoe alleles
$300,000
Massachusetts General Hospital · Boston, MA · 2025
Understanding human brain resilience to alzheimer's pathology
$300,000
Massachusetts General Hospital · Boston, MA · 2024
Understanding human brain resilience to alzheimer's pathology
$300,000
Massachusetts Institute of Technology · Cambridge, MA · 2024
Dissecting microglial state dynamics in alzheimer's disease
$300,000
Massachusetts General Hospital · Boston, MA · 2023
Understanding human brain resilience to alzheimer's pathology
$300,000
Massachusetts Institute of Technology · Cambridge, MA · 2023
Circuits: dissecting microglial state dynamics in alzheimer's disease
$300,000
Boston Children'S Hospital · Boston, MA · 2022
Nic: understanding the consequences of non-coding ad risk alleles on microglia function
$287,673
National Institute of Neurological Disorders & Stroke · Bethesda, MD · 2025
Bee: high-resolution mri of the brain borders
$287,500
Massachusetts General Hospital · Boston, MA · 2025
Bee: human 3d neuro-vascular interaction and meningeal lymphatics models with application to alzheimer's disease
$287,500
New York University School of Medicine · New York, NY · 2025
Nic: astrocyte inflammatory contributions to ad
$287,500
Regents of the University of California San Diego · La Jolla, CA · 2025
Nic: mechanisms mediating microglia sensing of peripheral inflammation
$287,500
Regents of the University of California San Diego · La Jolla, CA · 2025
Bee: how does vascular fatty acid metabolism regulate the pathophysiology of alzheimer's disease?
$287,500
Stanford University · Redwood City, CA · 2025
Bac: choroid plexus aging and alzheimer's disease
$287,500
University of Rochester · Rochester, NY · 2025
Bee: does slym failure compromise glymphatic clearance in alzheimer's disease?
$287,500
Washington University in St Louis · St Louis, MO · 2025
Bac: brain region and cell-type specific aging from accelerated to resilient trajectories
$287,500
Massachusetts General Hospital · Boston, MA · 2024
Bee: human 3d neuro-vascular interaction and meningeal lymphatics models with application to alzheimer's disease
$287,500
Massachusetts General Hospital · Boston, MA · 2024
Alzheimer's disease tau consortium: toxic consequences of early tau seeding
$287,500
Massachusetts General Hospital · Boston, MA · 2024
Mbc: microbial profiling of human brain and gut microbiomes in alzheimer's disease.
$287,500
National Institute of Neurological Disorders & Stroke · Bethesda, MD · 2024
Bee: high-resolution mri of the brain borders
$287,500
New York University School of Medicine · New York, NY · 2024
Neuroimmune consortium: astrocyte inflammatory contributions to alzheimer's disease
$287,500
University of California San Diego · La Jolla, CA · 2024
Bee: how does vascular fatty acid metabolism regulate the pathophysiology of alzheimer's disease?
$287,500
University of Rochester · Rochester, NY · 2024
Bee: does slym failure compromise glymphatic clearance in alzheimer's disease?
$287,500
Washington University in St Louis · St Louis, MO · 2024
Mbc: the role of gut microbial metabolism in tau-mediated neurodegeneration
$287,500
Boston University · Boston, MA · 2023
Apoe consortium: modulation of selective neuronal vulnerability in alzheimer's disease by apoe
$287,500
Brigham and Women'S Hospital · Boston, MA · 2023
Apoe consortium: apoe4-mediated dysfunction of cd8 t cell-microglia crosstalk in alzheimer's disease
$287,500
Brigham and Women'S Hospital · Boston, MA · 2023
Mbc: harnessing diet-microbe interactions to prevent alzheimer's disease pathogenesis
$287,500
Massachusetts General Hospital · Boston, MA · 2023
Mbc: microbial profiling of human brain and gut microbiomes in alzheimer's disease
$287,500
University of California San Diego · La Jolla, CA · 2023
Bee: identifying the blood-brain barrier changes during alzheimer's disease
$287,500
University of California San Diego · La Jolla, CA · 2023
Nic: mechanisms mediating microglia sensing of peripheral inflammation
$287,500
Washington University · St Louis, MO · 2023
Mbc: the role of gut microbial metabolism in tau-mediated neurodegeneration
$287,500
Weill Cornell · New York, NY · 2023
Bee: biochemical and functional analysis of csf and lymph following changes in brain fluid dynamics
$287,500
Brigham and Women'S · Boston, MA · 2022
Apoe consortium: apoe4-mediated dysfunction of cd8 t cell-microglia crosstalk in alzheimers disease
$287,500
Massachusetts General Hospital · Charlestown, MA · 2022
Nic: biomarker tool development in caf neuroimmune consortium
$287,500
University of California San Diego · La Jolla, CA · 2022
Bee: identifying the blood-brain barrier changes during alzheimers disease
$287,500
Weill Cornell · New York, NY · 2022
Bee: biochemical and functional analysis of csf and lymph following changes in brain fluid dynamics
$287,499
Washington University in St Louis · St Louis, MO · 2025
Bac: establishing isogenic models of human neuron aging and pathways relevant for alzheimer's disease
$287,493
University of California Irvine · Irvine, CA · 2023
Nic: examining the impact of peripherally derived human macrophages in ad pathogenesis
$287,490
University of California Irvine · Irvine, CA · 2025
Nic: examining the impact of peripherally derived human macrophages in ad pathogenesis
$287,477
Massachusetts Institute of Technology · Cambridge, MA · 2025
Bac: investigating lipidomic perturbations in the csf with age and alzheimer's disease progression: toward mechanistic insights and accessible lipid biomarkers
$287,276
University of Texas Southwestern Medical Center · Dallas, TX · 2024
Alzheimer's disease tau consortium: strain replication in mouse and cell models
$287,169
Massachusetts General Hospital · Boston, MA · 2023
Adtc: how do soluble tau species replicate?
$287,000
University of Texas Southwestern Medical Center · Dallas, TX · 2023
Adtc: role of vcp/p97 in tau prion replication
$287,000
University of Texas Southwestern Medical Center · Dallas, TX · 2022
Adtc: the role of vcp/p97 in tau prion replication
$286,595
Massachusetts General Hospital · Charlestown, MA · 2022
Adtc: how do soluble tau species replicate?
$286,559
Northwestern University · Chicago, IL · 2024
Alzheimer's disease tau consortium: the role of ab - induced membrane damage in tau pathology
$286,466
University of California Davis · Davis, CA · 2025
Nic: impact of ad polygenic risk score on microglial response to peripheral inflammation
$286,448
Northwestern University · Chicago, IL · 2023
Adtc: the role of a-induced membrane damage in tau pathology
$286,357
Northwestern · Chicago, IL · 2022
Adtc: the role of a-induced membrane damage in tau pathology
$285,952
University of Pennsylvania · Philadelphia, PA · 2024
Apoe: cell autonomous roles of protective apoe variants in microglia responding to amyloid pathology
$285,851
University of California Davis · Davis, CA · 2024
Neuroimmune consortium: impact of ad polygenic risk score on microglial response to peripheral inflammation
$284,678
University of Pennsylvania · Philadelphia, PA · 2025
Apoe consortium: cell autonomous roles of protective apoe variants in microglia responding to amyloid pathology
$275,500
Brigham and Women'S Hospital · Boston, MA · 2024
Mbc: harnessing diet-microbe interactions to prevent alzheimer's disease pathogenesis
$271,375
University of Alabama at Birmingham · Birmingham, AL · 2025
Expanding deep south inclusion in the uab adrc neuropathology core brain bank
$268,750
Duke University School of Medicine · Durham, NC · 2024
Plasma proteins, sex and alzheimer's diease: proteomewide analyses of the uk biobank and framingham heart study
$264,500
Boston Children'S Hospital · Boston, MA · 2025
Bee: neuroinflammation at the choroid plexus in alzheimer's disease (supplement)
$258,750
Massachusetts General Hospital · Boston, MA · 2025
Alzheimer's disease tau consortium: toxic consequences of early tau seeding (cfsf supplement)
$258,750
Massachusetts General Hospital · Boston, MA · 2025
Exploring novel drug candidates for alzheimer's disease through integrative pathway analysis and validation in 3d cellular models (cfsf supplement)
$258,750
University of Virginia · Charlottesville, VA · 2025
The role of planar cell polarity proteins in tau oligomer-induced synapse degeneration (cfsf supplement)
$258,750
Weill Medical College of Cornell University · New York, NY · 2025
A three-dimensional tissue model linking tau tangles, ab and microglial cd33- isoform state to gene- and isoform-expression dysregulation (cfsf supplement)
$258,750
Washington University in St Louis · St Louis, MO · 2024
Dissecting alzheimer's disease phenotypes in directly reprogrammed patient-derived neurons
$258,750
Massachusetts General Hospital · Boston, MA · 2023
Functional changes to cerebrospinal fluid immune cells resulting from bacillus calmette-gurin (bcg) vaccination in older adults with and without alzheimer's disease
$258,615
Gladstone Institutes · San Francisco, CA · 2025
Decoding protein transport across the blood-brain barrier to enable new alzheimer's therapies (cfsf supplement)
$258,573
Gladstone Institutes · San Francisco, CA · 2025
Developing cell-type-specific enhancer-aav vectors to characterize and restore ab- and tau-dependent circuit and cognitive deficits in humanized alzheimer's mouse models (cfsf supplement)
$252,077
Washington University · St Louis, MO · 2022
Apoe: assessing the added diagnostic value of peripheral apoe protein levels in current blood-based biomarker assays for cns amyloidosis
$252,076
Massachusetts General Hospital · Boston, MA · 2025
Menopause and related midlife risk factors and their impact on pathology and cognition - the whimsyad study
$250,000
The University of Chicago · Chicago, IL · 2024
Microbiome consortium: temporal relationships between gut dysbiosis, brain ab metabolism and microglia cell activation following antibiotic treatment
$250,000
University of Chicago · Chicago, IL · 2023
Mbc: temporal relationships between gut dysbiosis, brain ab metabolism and microglia cell activation following antibiotic treatment
$250,000
University of Southern California · Los Angeles, CA · 2023
Cellular and molecular studies of apoe regulation of blood-brain barrier, synaptic and neuronal functions and protection strategies in mouse models with and without alzheimer's pahtology
$250,000
Weill Cornell · New York, NY · 2023
Development of human cgas inhibitors to treat alzheimer's disease
$250,000
Harvard Medical School · Boston, MA · 2022
Nic: assessing the links between the ms4a risk genes, microglia, and alzheimers disease

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Source: IRS Form 990, Schedule I, as filed by this organization. These are grants already paid. Grants paid directly to individuals are reported to the IRS only as totals, so they do not appear as named lines here.