Funding search · Alzheimer'S Disease Research Foundation · grants

Alzheimer'S Disease Research Foundation: all 448 grants

Largest first · $100.1M across 2022–2025 · back to the overview

$250,000
Massachusetts General Hospital · Charlestown, MA · 2022
Creation of a fibroblast/ips cell bank to facilitate peripheral/brain comparisons, and allow molecular investigations into molecular mechanisms underlying differences in disease aggressiveness
$250,000
University of California Irvine · Irvine, CA · 2022
Nic: examining the role of human microglia in the transition between parenchymal and vascular beta-amyloid pathology
$250,000
University of California San Diego · La Jolla, CA · 2022
Nic: leveraging enhancer landscapes to decode ad risk alleles in microglia
$250,000
Weill Cornell · New York, NY · 2022
Development of human cgas inhibitors to treat alzheimers disease
$248,980
Beth Israel Deaconess Medical Center · Boston, MA · 2022
Circuits: aunified approach to actionable alzheimers disease signatures
$246,804
Northwestern · Chicago, IL · 2022
Single nucleus rna sequencing analysis of ace1 r1284q knockin mice
$243,407
University of Michigan · Ann Arbor, MI · 2022
Neurobiological basis of cognitive impairment in african americans: deep phenotyping of older african americans at risk of dementia
$234,709
University of Southern California · Los Angeles, CA · 2023
Protection against apoe4 with longevity-promoting interventions
$230,590
Massachusetts General Hospital · Charlestown, MA · 2022
Ad4: high-throughput drug screening for alzheimer's disease using 3d human neural culture systems
$230,000
Icahn School of Medicine at Mount Sinai · New York, NY · 2025
Investigating the pathogenetic role of microglial mef2c in alzheimer's disease across the lifespan: developmental priming vs. Adult response to injury
$230,000
Massachusetts General Hospital · Boston, MA · 2025
Adam10 cleavage of app: physiological function in brain and therapeutic potential for alzheimer's disease
$230,000
Mayo Clinic Jacksonville · Jacksonville, FL · 2025
Unraveling mixed pathology and its impact on the proteome in alzheimer's disease
$230,000
President and Fellows of Harvard College · Cambridge, MA · 2025
Moving the cure alzheimer genome project beyond simple associations: integrating functional information, fine-mapping and causal inference approaches into the family-based analysis of the cure alzheimer whole-genome seq… read allMoving the cure alzheimer genome project beyond simple associations: integrating functional information, fine-mapping and causal inference approaches into the family-based analysis of the cure alzheimer whole-genome sequencing (wgs) family study less
$230,000
Regents of the University of California San Diego · La Jolla, CA · 2025
App gene dose-mediated dysregulation of the endolysosomal network acts compromise synaptic structure and function leading to alzheimer disease in down syndrome
$230,000
The Broad Institute · Cambridge, MA · 2025
Investigating alzheimer's disease-associated membrane biology in microglia and neurons
$230,000
University of California Irvine · Irvine, CA · 2025
Engineered car-macrophages to clear tau
$230,000
University of Texas Southwestern Medical Center · Dallas, TX · 2025
Engineered car-macrophages to clear tau
$230,000
Massachusetts General Hospital · Boston, MA · 2024
Selective vulnerability in posterior cortical atrophy
$230,000
Massachusetts General Hospital · Boston, MA · 2024
Adam10 cleavage of app: physiological function in brain and therapeutic potential for alzheimer's disease
$230,000
Memorial Sloan Kettering Cancer Center · New York, NY · 2024
The role of ifitm3 and -secretase in microglia
$230,000
President and Fellows of Harvard College · Cambridge, MA · 2024
Harvard t.h. Chan school of public health-moving the cure alzheimer genome project beyond simple associations: integrating functional information, fine-mapping and causal inference approaches into the family-based analy… read allHarvard t.h. Chan school of public health-moving the cure alzheimer genome project beyond simple associations: integrating functional information, fine-mapping and causal inference approaches into the family-based analysis of the cure alzheimer whole-genome sequencing (wgs) family study less
$230,000
The Broad Institute · Cambridge, MA · 2024
Investigating alzheimer's disease-associated membrane biology in microglia and neurons
$230,000
University of California Irvine · Irvine, CA · 2024
Endogenous human antibodies associated with alzheimer's disease
$230,000
Massachusetts General Hospital · Boston, MA · 2023
Bee: a 3d in-vitro neuro-vascular human brain model with meningeal lymphatics for elucidating mechanisms underlying alzheimer's disease
$230,000
Memorial Sloan Kettering Cancer Center · New York, NY · 2023
The role of ifitm3 and y-secretase in microglia
$230,000
University of California Irvine · Irvine, CA · 2023
Endogenous human antibodies associated with alzheimer's disease
$230,000
University of California San Diego · La Jolla, CA · 2023
App gene dose-mediated dysregulation of the endolysosomal network acts compromise synaptic structure and function leading to alzheimer's disease in down syndrome
$230,000
University of Connecticut · Farmington, CT · 2023
Ad pathophysiology alters the level of electrical and chemical synapse coupling in the network of gabaergic pv+ interneurons early in disease course
$230,000
University of Texas Southwestern Medical Center · Dallas, TX · 2023
Rna as a determinant of tau seeding
$230,000
University of Connecticut · Farmington, CT · 2022
Ad pathophysiology alters the level of electrical and chemical synapse coupling in the network of gabaergic pv+ interneurons early in disease course
$230,000
University of Texas Southwestern Medical Center · Dallas, TX · 2022
Rna and tau seed formation
$229,994
Duke University School of Medicine · Durham, NC · 2023
Utility of blood based markers for predicting aria and its course in mci and ad subjects undergoing routine clinical treatment with amyloid-directed antibodies
$229,033
University of Chicago · Chicago, IL · 2022
Temporal relationships between gut dysbiosis and microglia cell activation following antibiotic treatment
$228,900
Brigham and Women'S Hospital · Boston, MA · 2025
Do classical complement activation and the route of administration of anti-amyloid antibodies contribute to vascular side effects known as aria?
$228,779
Brigham and Women'S Hospital · Boston, MA · 2024
Do classical complement activation and the route of administration of anti-amyloid antibodies contribute to vascular side effects known as aria?
$227,410
University of Southern California · Los Angeles, CA · 2024
Protection against alzheimer's with longevity-promoting intervention 17a-estradiol
$225,000
Houston Methodist · Houston, TX · 2022
Ad4: uncovering the molecular mechanism of selected drug candidates derived from systematics alzheimers drug repositioning
$220,071
Harvard Medical School · Cambridge, MA · 2023
Analytical and statistical tools for sequence analysis for alzheimer's disease
$219,578
Washington University in St Louis · St Louis, MO · 2024
Mapping the x chromosome multi-ome in alzheimer's and parkinson's disease
$219,535
University of Southern California · Los Angeles, CA · 2022
Air pollution and ad risk interact with premature aging of neural stem cells and apoe alleles
$217,327
Mount Sinai · New York, NY · 2022
Microglial-specific inpp5d knockdown modulates behavior, amyloidosis, and tauopathy in alzheimer's mouse models
$216,287
The University of Chicago · Chicago, IL · 2024
Identifying the sex-specific roles of the gutmicrobiome-brain axis in a mouse model of ab amyloidosis
$210,962
New York University School of Medicine · New York, NY · 2025
Mechanisms of astrocyte-derived lipid toxicity in alzheimer's disease
$210,871
University of Chicago · Chicago, IL · 2022
Identifying the sex-specific roles of the gut-microbiome-brain axis in a mouse model of ab amyloidosis
$208,033
New York University · New York, NY · 2023
Mechanisms of astrocyte-derived lipid toxicity in alzheimer's disease
$204,656
Duke University School of Medicine · Durham, NC · 2025
Contributions of il34 signaling to microglial function and alzheimer's pathology in mice
$204,238
Yale · New Haven, CT · 2022
Bee: cns fluid homeostasis and waste clearance in alzheimers disease characterized by mri
$204,081
Yale University · New Haven, CT · 2023
Bee: cns fluid homeostasis and waste clearance in alzheimer's disease characterized by mri
$201,501
Columbia University · New York, NY · 2023
Neuroproteasomes mechanistically connect apoe isoforms to endogenous tau aggregation
$201,279
Columbia University · New York, NY · 2024
Neuroproteasomes mechanistically connect apoe isoforms to endogenous tau aggregation
$201,251
University of Michigan · Ann Arbor, MI · 2025
Morphological, electrophysiological, and transcriptional characterization of single neurons from resilient and susceptible models of human ad
$201,250
Augusta University Research Institute · Augusta, GA · 2025
The impact of soluble dietary fiber on tau-mediated neurodegeneration in a mouse model of tauopathy
$201,250
Beth Israel Deaconess Medical Center · Boston, MA · 2025
Integrating single-cell genomics for pathways to protection and resilience against alzheimer's disease
$201,250
Brigham and Women'S Hospital · Boston, MA · 2025
Viral infections and alzheimer's disease risk in women
$201,250
Carnegie Mellon University · Pittsburgh, PA · 2025
Interpreting alzheimer's disease-associated genetic variation at enhancer regions
$201,250
Columbia University · New York, NY · 2025
Semaphorin regulation of disease-associated microglia in alzheimer's disease
$201,250
Columbia University · New York, NY · 2025
Noncoding translation feedback loop in alzheimer's disease
$201,250
Emory University · Atlanta, GA · 2025
Mitochondrial alzheimer's risk factors control apoe expression and secretion
$201,250
Gladstone Institutes · San Francisco, CA · 2025
Developing cell-type-specific enhancer-aav vectors to characterize and restore ab- and tau-dependent circuit and cognitive deficits in humanized alzheimer's mouse model
$201,250
Gladstone Institutes · San Francisco, CA · 2025
Decoding protein transport across the blood-brain barrier to enable new alzheimer's therapies
$201,250
Icahn School of Medicine at Mount Sinai · New York, NY · 2025
Investigating the association between clonal hematopoiesis and alzheimer's disease
$201,250
Icahn School of Medicine at Mount Sinai · New York, NY · 2025
Investigating mef2c transcription factor as therapeutic target to reprogram pathological microglial states in alzheimer's disease
$201,250
Icahn School of Medicine at Mount Sinai · New York, NY · 2025
Role of psychosocial stress in alzheimer's disease
$201,250
Johns Hopkins University · Baltimore, MD · 2025
From molecular heterogeneity to predictive medicine: transforming neurodegenerative disease research through spatial multi-omics and interpretable ai
$201,250
Johns Hopkins University · Baltimore, MD · 2025
A temporally aligned multimodal framework for individualized alzheimer's disease risk assessment and deep learning-driven prognosis
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Development of a flap-targeted neuroimmune pet tracer for imaging microglia in ad
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Interneuron therapy for alzheimer's disease
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Circuit dynamics in apoe4 mice
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Identifying sex-aware x-chromosome targets for preclinical alzheimer's disease
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Centenarian microglia reveal a neprilysin-dependent mechanism of resilience in alzheimer's disease
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Exploring novel drug candidates for alzheimer's disease through integrative pathway analysis and validation in 3d cellular models
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Rin3 and bin1 interaction connects endosomal pathology with amyloid pathology
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Engineering a human region-specific system to probe apoe-linked cellular vulnerability and resilience in alzheimer's disease
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Precision gene therapy targeting microglia in alzheimer's disease
$201,250
Massachusetts General Hospital · Boston, MA · 2025
Tau and b-amyloid are innate immune antimicrobial peptides in the brain
$201,250
Mayo Clinic Jacksonville · Jacksonville, FL · 2025
Linking sleep dysfunction to tau-related degeneration across ad variants
$201,250
Mayo Clinic Jacksonville · Jacksonville, FL · 2025
Elucidating the protective effects of apoe2 in the presence of apoe 4 gene allele in animal models
$201,250
Mayo Clinic Jacksonville · Jacksonville, FL · 2025
Evaluating the contribution of tdp-43 dysfunction and cryptic mis-splicing to ad pathogenesis
$201,250
Mayo Clinic Jacksonville · Jacksonville, FL · 2025
The multi-omic roadmap to neuronal senescence in alzheimer's disease
$201,250
Mayo Clinic Rochester · Rochester, MN · 2025
Bridging the gap: sex-specific drivers of senescence underlying neurodegeneration
$201,250
Memorial Sloan Kettering Cancer Center · New York, NY · 2025
Development and mechanism of autophagy activators for treatment of alzheimer's disease
$201,250
New York University School of Medicine · New York, NY · 2025
Viral infections and alzheimer's disease risk in women
$201,250
New York University School of Medicine · New York, NY · 2025
Midlife autoantibody profiles and the risk of late-onset alzheimer's disease in women
$201,250
Northwestern University · Chicago, IL · 2025
Role of tau in presynaptic dysfunction during the cellular phase of alzheimer's disease
$201,250
Northwestern University · Chicago, IL · 2025
Sex-specific mechanisms of neuroinflammation in the alzheimer's disease hypothalamus
$201,250
President and Fellows of Harvard College · Cambridge, MA · 2025
Meningeal tregs in individuals with vs without alzheimer's disease
$201,250
Regents of the University of California San Diego · La Jolla, CA · 2025
Son-dependent nuclear speckle rejuvenation: a novel proteostasis-based therapeutic strategy for alzheimer's disease
$201,250
Regents of the University of California San Diego · La Jolla, CA · 2025
Dysregulation of signaling on post synaptic density scaffolds in alzheimer's disease
$201,250
The Regents of the University of California San Francisco · San Francisco, CA · 2025
Role of platelet-derived factors in ameliorating alzheimer's disease pathology
$201,250
The Regents of the University of California San Francisco · San Francisco, CA · 2025
Probing the molecular underpinnings of how g protein-coupled receptor adgrg1 mediates protective responses to alzheimer's disease
$201,250
The Regents of the University of California San Francisco · San Francisco, CA · 2025
Neuronal mechanisms driving synapse loss in alzheimer's disease
$201,250
The Salk Institute for Biological Studies · La Jolla, CA · 2025
The role of astrocyte-secreted igfbp2 in the progression of alzheimer's disease
$201,250
University of California Davis · Davis, CA · 2025
Deciphering phosphorylation-dependent tau envelope dysfunction to prevent alzheimer's neurodegeneration
$201,250
University of South Florida · Tampa, FL · 2025
Bin1 in microglial heterogeneity along ad progression and microglial function
$201,250
University of Texas Health Science Center at San Antonio · San Antonio, TX · 2025
How do microglia contribute to the spread of tau pathology in alzheimer's disease?
$201,250
University of Texas Health Science Center at San Antonio · San Antonio, TX · 2025
Cognitively healthy nonagenarians in the cross cohort collaboration (ccc)
$201,250
University of Texas Health Science Center at San Antonio · San Antonio, TX · 2025
Digital neuropathology infrastructure for precision medicine in south texas hispanic ad/adrd populations
$201,250
University of Virginia · Charlottesville, VA · 2025
Elucidating the role of emerging genomic stress sensors in ad
$201,250
University of Virginia · Charlottesville, VA · 2025
Impact of dna damage-mediated sting activation on myelin function in an alzheimer's disease animal model
$201,250
University of Virginia · Charlottesville, VA · 2025
Microglial mitochondrial dysfunction and tau toxicity in alzheimer's disease